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How to get fromSanford to Roanokeby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

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There are 7 ways to get from Sanford to Roanoke by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Orlando Sanford

    best
    1. Fly from Orlando Sanford (SFB) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane SFB - ROA
    2h 52m
    $71–372

  2. Train to Orlando, fly

    cheapest
    1. Take the train from Sanford to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane MCO - ROA
    7h 20m
    $69–351

  3. Bus

    1. Take the bus from Deltona to Richmondbus bus
    2. Take the bus from Richmond to Lynchburg Transit Centerbus bus
    3. Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus bus
    20h 26m
    $150–246

  4. Train (Amtrak)

    1. Take the train from Deland to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the train from Greensboro to Lynchburgtrain train
    4. Take the train from Lynchburg to Roanoketrain train
    21h 40m
    $251–553

  5. Drive 664.9 mi

    1. Drive from Sanford to Roanokecar car 664.9 mi
    11h 51m
    $122–176

  6. Fly from Daytona Beach International Airport

    1. Fly from Daytona Beach International Airport (DAB) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane DAB - ROA
    9h 20m
    $101–512

  7. Train, bus

    1. Take the train from Deland to Fredericksburg Amtraktrain train Silver Meteor
    2. Take the bus from Fredericksburg Bus Stop to Roanoke Bus Stopbus bus Greyhound US0600
    23h 2m
    $270–608

Sanford to Roanoke by train (Amtrak)

Calendar7Weekly Trains
Duration21h 40mAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

Map of how to get from Sanford to Roanoke.ExpandLaunch map view
  • Distance: 602.3 mi
  • Duration: 2h 52m

What companies run services between Sanford, FL, USA and Roanoke, VA, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Roanoke Regional Airport-Woodrum Field (ROA) twice a week. Alternatively, you can take a vehicle from Sanford to Roanoke Bus Stop via Deltona, Richmond, Richmond, and Lynchburg Transit Center in around 20h 26m.

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Bus operators

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