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How to get fromSanibel Island to Charlotteby plane, bus (Flixbus), bus, train, or car

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There are 5 ways to get from Sanibel Island to Charlotte by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT)plane plane RSW - CLT
    3h 21m
    $199–743

  2. Drive 689.3 mi

    cheapest
    1. Drive from Sanibel Island to Charlottecar car 689.3 mi
    12h 14m
    $126–182

  3. Bus via University

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    16h 46m
    $196–314

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    24h 42m
    $364–702

  5. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    18h 50m
    $137–229

Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT) flights

Calendar58Weekly Planes
Duration3h 44mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Sanibel Island to Charlotte.ExpandLaunch map view
  • Distance: 634 mi
  • Duration: 3h 21m

What companies run services between Sanibel Island, FL, USA and Charlotte, NC, USA?

American Airlines, Delta, and Southwest Airlines fly from Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT) every 4 hours. Alternatively, you can take a vehicle from Sanibel Island to Charlotte Bus Station via Fort Myers 7-11, University of South Florida, and Orlando Bus Station in around 16h 46m.

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