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How to get fromSanibel Island to Destinby plane, bus, taxi, or car

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There are 5 ways to get from Sanibel Island to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane plane RSW - VPS
    5h 2m
    $211–625

  2. Drive 516.9 mi

    cheapest
    1. Drive from Sanibel Island to Destincar car 516.9 mi
    10h 4m
    $95–137

  3. Bus, taxi

    1. Take the bus from Fort Myers to Tallahassee FSUbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    21h 21m
    $340–523

  4. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 42m
    $311–740

  5. Fly to Pensacola International Airport, taxi

    1. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 34m
    $566–1,050

Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar61Weekly Planes
Duration5h 39mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Sanibel Island to Destin.ExpandLaunch map view
  • Distance: 439.8 mi
  • Duration: 5h 2m

What companies run services between Sanibel Island, FL, USA and Destin, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) every 3 hours.

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