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How to get fromSanibel Island to Floridaby bus (Flixbus), bus, train, or car

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There are 5 ways to get from Sanibel Island to Florida by bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers to Tampa USFbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville to Jacksonvillebus bus
    8h 26m
    $133–205

  2. Drive 309.3 mi

    cheapest
    1. Drive from Sanibel Island to Jacksonvillecar car 309.3 mi
    5h 57m
    $57–82

  3. Bus, train

    1. Take the bus from Fort Myers to Tampa USFbus bus Miami–Tampa / ...
    2. Take the train from Tampa to Jacksonvilletrain train Floridian
    11h 10m
    $183–318

  4. Bus via Orlando

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus FlixBus N2472 / ...
    11h 45m
    $81–132

  5. Bus, train via South Fort Myers Transfer/P&R

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Jacksonvilletrain train Floridian
    12h 42m
    $122–231

Questions & Answers

Map of how to get from Sanibel Island to Florida.ExpandLaunch map view
  • Distance: 345.8 mi
  • Duration: 8h 26m

What companies run services between Sanibel Island, FL, USA and Florida, USA?

You can take a vehicle from Sanibel Island to Jacksonville via Fort Myers, University of South Florida, and Gainesville in around 8h 26m.

Train operators
Bus operators

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