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How to get fromSanibel Island to Gainesvilleby bus, car, plane, or bus (Flixbus)

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There are 6 ways to get from Sanibel Island to Gainesville by bus, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Drbus bus Miami
    5h 46m
    $133–206

  2. Drive 246.6 mi

    cheapest
    1. Drive from Sanibel Island to Gainesvillecar car 246.6 mi
    4h 59m
    $45–65

  3. Fly Ft. Myers to Gainesville Regional Airport

    1. Fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV)plane plane RSW - GNV
    5h 51m
    $173–582

  4. Bus via University

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus Miami
    2. Take the bus from University of South Florida to Gainesvillebus bus FlixBus N2467
    6h 1m
    $122–186

  5. Fly Ft. Myers to Orlando, bus

    1. Fly from Ft. Myers (RSW) to Orlando (MCO)plane plane RSW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    5h 13m
    $397–747

  6. Bus to Miami International Airport, fly to Gainesville Regional Airport

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Gainesville Regional Airport (GNV)plane plane MIA - GNV
    7h 6m
    $150–438

Ft. Myers (RSW) to Gainesville Regional Airport (GNV) flights

Calendar55Weekly Planes
Duration6hAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Sanibel Island to Gainesville.ExpandLaunch map view
  • Distance: 279.8 mi
  • Duration: 5h 46m

What companies run services between Sanibel Island, FL, USA and Gainesville, FL, USA?

RedCoach operates a bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Dr once daily. Tickets cost $60–120 and the journey takes 5h 10m. Alternatively, Delta and American Airlines fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV) every 4 hours.

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