There are 3 ways to get from Sanibel Island to Key Biscayne by taxi, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, bus
best- Take the taxi from Sanibel Island to Naples, FLtaxi
- Take the bus from Naples, FL to Miami Airportbus Tallahassee
4h 18m$161–197Drive 162.6 mi
cheapest- Drive from Sanibel Island to Key Biscaynecar 162.6 mi
3h 6m$30–43Bus (Flixbus)
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus FlixBus 2421
4h 47m$84–106
Comparing Your Travel Options
The cheapest way to get from Sanibel Island to Key Biscayne is to drive which costs $29 - $45 and takes 3h 6m.
The fastest way to get from Sanibel Island to Key Biscayne is to drive which takes 3h 6m and costs $29 - $45.
No, there is no direct bus from Sanibel Island to Key Biscayne. However, there are services departing from Fort Myers Bus Stop and arriving at Crandon Bd & Harbor Dr via Brickell Station. The journey, including transfers, takes approximately 4h 47m.
The distance between Sanibel Island and Key Biscayne is 171 miles. The road distance is 163.6 miles.
The best way to get from Sanibel Island to Key Biscayne without a car is to taxi and bus which takes 4h 18m and costs $160 - $200.
It takes approximately 4h 18m to get from Sanibel Island to Key Biscayne, including transfers.
Sanibel Island to Key Biscayne bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Sanibel Island to Key Biscayne bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Sanibel Island to Key Biscayne is 164 miles. It takes approximately 3h 6m to drive from Sanibel Island to Key Biscayne.
There are 4999+ hotels available in Key Biscayne.
What companies run services between Sanibel Island, FL, USA and Key Biscayne, FL, USA?
Flixbus USA operates a bus from Fort Myers Bus Stop to Miami Airport Station 3 times a day. Tickets cost $23–35 and the journey takes 3h 5m.
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide




