There are 4 ways to get from Sanibel Island to Key West by ferry, bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
4h 17m$164–171Drive 280.8 mi
cheapest- Drive from Sanibel Island to Key Westcar 280.8 mi
6h 5m$52–74Bus
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
12h 37m$69–118Fly
- Fly from Ft. Myers (RSW) to Key West International Airport (EYW)plane RSW - EYW
5h 11m$557–903
Ft. Myers (RSW) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Sanibel Island to Key West is to drive which costs $50 - $75 and takes 6h 5m.
The fastest way to get from Sanibel Island to Key West is to ferry which takes 4h 17m and costs $160 - $175.
No, there is no direct bus from Sanibel Island to Key West. However, there are services departing from Mcgregor Blvd @ Davis Rd and arriving at N Roosevelt & 3rd Street via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 12h 37m.
No, there is no direct ferry from Sanibel Island to Key West. However, there are services departing from Fort Myers Beach, FL and arriving at Key West, FL via . The journey, including transfers, takes approximately 4h 17m.
The distance between Sanibel Island and Key West is 148 miles. The road distance is 282.5 miles.
The best way to get from Sanibel Island to Key West without a car is to ferry which takes 4h 17m and costs $160 - $175.
It takes approximately 4h 17m to get from Sanibel Island to Key West, including transfers.
Sanibel Island to Key West bus services, operated by FlixBus-us, depart from Fort Myers Bus Stop station.
The best way to get from Sanibel Island to Key West is to bus which takes 12h 37m and costs $65 - $120. Alternatively, you can fly, which costs $550 - $950 and takes 5h 11m.
Sanibel Island to Key West bus services, operated by FlixBus-us, arrive at Miami Airport Station.
What companies run services between Sanibel Island, FL, USA and Key West, FL, USA?
Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a vehicle from Sanibel Island to N Roosevelt & 3rd Street via Mcgregor Blvd @ Davis Rd, South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 37m.
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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More Questions & Answers
Yes, the driving distance between Sanibel Island to Key West is 282 miles. It takes approximately 6h 5m to drive from Sanibel Island to Key West.
There are 947+ hotels available in Key West.