There are 4 ways to get from Sanibel Island to Mobile by plane, bus (Flixbus, Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mobile Regional Airport
best- Fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB)plane RSW - MOB
5h 7m$179–552Drive 621 mi
cheapest- Drive from Sanibel Island to Mobilecar 621 mi
11h 10m$107–154Bus
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Tallahasseebus
- Take the bus from Tallahassee to Mobile Bus Stationbus
17h 30m$160–240Fly to Pensacola International Airport, taxi
- Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane RSW - PNS
- Take the taxi from Pensacola-Airport-PNS to Mobiletaxi
5h 52m$264–582
Ft. Myers (RSW) to Mobile Regional Airport (MOB) flights
Comparing Your Travel Options
The cheapest way to get from Sanibel Island to Mobile is to drive which costs $100 - $160 and takes 11h 10m.
The fastest way to get from Sanibel Island to Mobile is to fly which takes 5h 7m and costs $170 - $550.
No, there is no direct bus from Sanibel Island to Mobile. However, there are services departing from Fort Myers Bus Stop and arriving at Govt EB at Franklin St via Tampa Bus Station, Tallahassee and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 17h 30m.
The distance between Sanibel Island and Mobile is 527 miles. The road distance is 624.6 miles.
The best way to get from Sanibel Island to Mobile without a car is to bus which takes 17h 30m and costs $160 - $240.
It takes approximately 5h 7m to get from Sanibel Island to Mobile, including transfers.
Sanibel Island to Mobile bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Sanibel Island to Mobile is to fly which takes 5h 7m and costs $170 - $550. Alternatively, you can bus, which costs $160 - $240 and takes 17h 30m.
Sanibel Island to Mobile bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
Yes, the driving distance between Sanibel Island to Mobile is 625 miles. It takes approximately 11h 10m to drive from Sanibel Island to Mobile.
What companies run services between Sanibel Island, FL, USA and Mobile, AL, USA?
Delta, United Airlines, and American Airlines fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a vehicle from Sanibel Island to Govt EB at Franklin St via Fort Myers Bus Stop, Tampa Bus Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 17h 30m.
- Website
- delta.com
Flights from Ft. Myers to Mobile Regional Airport via Atlanta
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $80–430
Flights from Ft. Myers to Pensacola International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $70–370
- Website
- aa.com
Flights from Ft. Myers to Mobile Regional Airport via Charlotte
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $100–490
Flights from Ft. Myers to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $120–600
Flights from Ft. Myers to Pensacola International Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $85–420
- Website
- united.com
Flights from Ft. Myers to Mobile Regional Airport via Houston
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $110–550
Flights from Ft. Myers to Mobile Regional Airport via Washington Dulles
- Ave. Duration
- 8h 40m
- When
- Every day
- Estimated price
- $130–600
Flights from Ft. Myers to Pensacola International Airport via Houston
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $100–460
- Website
- southwest.com
Flights from Ft. Myers to Pensacola International Airport via Orlando
- Ave. Duration
- 5h 35m
- When
- Monday to Friday
- Estimated price
- $55–330
Flights from Ft. Myers to Pensacola International Airport via Nashville
- Ave. Duration
- 6h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–420
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tampa Bus Station to Tallahassee
- Ave. Duration
- 5h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Tallahassee to Mobile Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $45–75
- Website
- Greyhound
- Ave. Duration
- 58 min
- Estimated price
- $140–170
Able Shuttle and Taxi
- Phone
- +1 850-607-0209
Choice Taxi
- Phone
- +1 850-529-1806
- Website
- mychoicetaxi.com
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Booking & Getting There
There are 211+ hotels available in Mobile.