Rome2Rio

How to get fromSanibel Island to New Orleansby plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to New Orleans

See all options

There are 5 ways to get from Sanibel Island to New Orleans by plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY)plane plane RSW - MSY
    3h 47m
    $327–893

  2. Bus #2

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    23h 5m
    $134–254

  3. Bus via Gainesville

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    20h 26m
    $201–341

  4. Drive 763.6 mi

    1. Drive from Sanibel Island to New Orleanscar car 763.6 mi
    13h 29m
    $140–202

  5. Bus

    1. Take the bus from Fort Myers 7-11 to Tallahassee, FLbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    21h 10m
    $232–405

Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY) flights

Calendar35Weekly Planes
Duration4h 1mAverage Duration
Ticket$109Cheapest Price
See schedules

Questions & Answers

Map of how to get from Sanibel Island to New Orleans.ExpandLaunch map view
  • Distance: 606 mi
  • Duration: 3h 47m

What companies run services between Sanibel Island, FL, USA and New Orleans, LA, USA?

Breeze Airways, Southwest Airlines, and Delta fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY) 5 times a day. Alternatively, you can take a vehicle from Sanibel Island to New Orleans Bus Station via Fort Myers 7-11, University of South Florida, Gainesville, Tallahassee, and Mobile Bus Station in around 20h 26m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers