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How to get fromSanibel Island to North Carolinaby plane, bus (Flixbus), bus, train, or car

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There are 7 ways to get from Sanibel Island to North Carolina by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilmington International Airport

    best
    1. Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)plane plane RSW - ILM
    2h 40m
    $320–657

  2. Drive 689.3 mi

    cheapest
    1. Drive from Sanibel Island to Charlottecar car 689.3 mi
    12h 14m
    $126–182

  3. Bus via University

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    16h 46m
    $196–312

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    25h 6m
    $356–700

  5. Fly to Charlotte Douglas International Airport

    1. Fly from Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT)plane plane RSW - CLT
    3h 21m
    $189–743

  6. Fly to Raleigh-Durham International Airport

    1. Fly from Ft. Myers (RSW) to Raleigh-Durham International Airport (RDU)plane plane RSW - RDU
    4h 3m
    $179–443

  7. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    18h 50m
    $132–229

Ft. Myers (RSW) to Wilmington International Airport (ILM) flights

Calendar38Weekly Planes
Duration4h 7mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Sanibel Island to North Carolina.ExpandLaunch map view
  • Distance: 610.2 mi
  • Duration: 2h 40m

What companies run services between Sanibel Island, FL, USA and North Carolina, USA?

Breeze Airways, American Airlines, and Delta fly from Ft. Myers (RSW) to Wilmington International Airport (ILM) 5 times a day. Alternatively, you can take a vehicle from Sanibel Island to Charlotte Bus Station via Fort Myers 7-11, University of South Florida, and Orlando Bus Station in around 16h 46m.

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