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How to get fromSanibel to Destinby taxi, plane, bus, car, or train

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There are 9 ways to get from Sanibel to Destin by taxi, plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Ft. Myers, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane plane RSW - VPS
    4h 54m
    $202–620

  2. Drive  517.9 mi

    cheapest
    1. Drive from Sanibel to Destincar car 517.9 mi
    10h 6m
    $95–137

  3. Bus, taxi

    1. Take the bus from Fort Myers 7-11 to Tallahassee, FLbus bus
    2. Take the bus from Tallahassee to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    22h 14m
    $407–539

  4. Taxi to Ft. Myers, fly to Pensacola International Airport, taxi

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 14m
    $242–555

  5. Taxi to Ft. Myers, fly to Northwest Florida Beaches International Airport, taxi

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    3. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    6h 8m
    $297–745

  6. Bus to Miami International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    6h 44m
    $202–530

  7. Bus, taxi via Sandy Springs

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    23h 51m
    $357–481

  8. Bus, taxi via Atlanta

    1. Take the bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Drbus bus
    2. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    4. Take the bus from La Grange Bus Station to Mobilebus bus
    5. Take the bus from Loxley to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    24h 6m
    $385–519

  9. Taxi, bus, train

    1. Take the taxi from Sanibel to Fort Myers Amtrak Bus Stoptaxi taxi
    2. Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus bus
    3. Take the train from Orlando to Jacksonvilletrain train
    4. Take the bus from Jacksonville to La Grange Bus Stationbus bus
    5. Take the bus from La Grange Bus Station to Mobilebus bus
    6. Take the bus from Loxley to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    27h 32m

Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar59Weekly Planes
Duration5h 11mAverage Duration
Ticket$89Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sanibel to Destin.ExpandLaunch map view
  • Distance: 440.8 mi
  • Duration: 4h 54m

What companies run services between Sanibel, FL, USA and Destin, FL, USA?

There is no direct connection from Sanibel to Destin. However, you can take the taxi to Ft-Myers-Airport-RSW airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can take the taxi to Fort Myers 7-11, take the bus to Tallahassee, FL, take the bus to Tallahassee - FSU - Old St Augustine at Intramural Field, take the bus to C.K. Steele Plaza Gate 21, take the bus to Montgomery Intermodal Center, take the taxi to Montgomery, take the bus to Mobile, take the bus to Crestview, then take the taxi to Destin.

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