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How to get fromSanibel to Destinby taxi, plane, bus, or car

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There are 6 ways to get from Sanibel to Destin by taxi, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane plane RSW - VPS
    5h 4m
    $214–629

  2. Drive 517.9 mi

    cheapest
    1. Drive from Sanibel to Destincar car 517.9 mi
    10h 6m
    $95–137

  3. Bus, taxi via Gainesville

    1. Take the bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Drbus bus
    2. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    22h 28m
    $338–526

  4. Taxi, fly to Northwest Florida Beaches International Airport

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    3. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 44m
    $314–744

  5. Taxi, fly to Pensacola International Airport

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 36m
    $569–1,054

  6. Bus, taxi

    1. Take the bus from Fort Myers 7-11 to Tallahassee, FLbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    22h 43m
    $344–528

Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar61Weekly Planes
Duration5h 39mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Sanibel to Destin.ExpandLaunch map view
  • Distance: 440.8 mi
  • Duration: 5h 4m

What companies run services between Sanibel, FL, USA and Destin, FL, USA?

There is no direct connection from Sanibel to Destin. However, you can take the taxi to Ft-Myers-Airport-RSW airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can take the taxi to Fort Myers 7-11, take the bus to University of Florida - 1956 Gale Lemerand Dr, take the bus to Tallahassee - FSU - Old St Augustine at Intramural Field, take the bus to C.K. Steele Plaza Gate 21, take the bus to Mobile Bus Station, walk to Govt EB at Greyhound Bus Station, take the line 9 bus to Govt Near Royal St, walk to Mobile, take the bus to Crestview, then take the taxi to Destin.

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