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How to get fromSanibel to Gainesvilleby bus, car, taxi, or plane

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There are 5 ways to get from Sanibel to Gainesville by bus, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Drbus bus Miami
    5h 48m
    $132–175

  2. Drive  247.6 mi

    cheapest
    1. Drive from Sanibel to Gainesvillecar car 247.6 mi
    5h 1m
    $43–62

  3. Taxi to Ft. Myers, fly to Gainesville Regional Airport

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV)plane plane RSW - GNV
    6h
    $154–517

  4. Taxi to Ft. Myers, fly to Orlando, bus

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Orlando (MCO)plane plane RSW - MCO
    3. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    5h 17m
    $148–467

  5. Bus to Miami International Airport, fly to Gainesville Regional Airport

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Gainesville Regional Airport (GNV)plane plane MIA - GNV
    7h 11m
    $149–407

Ft. Myers (RSW) to Gainesville Regional Airport (GNV) flights

Calendar47Weekly Planes
Duration4h 59mAverage Duration
Ticket$82Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sanibel to Gainesville.ExpandLaunch map view
  • Distance: 280.8 mi
  • Duration: 5h 48m

What companies run services between Sanibel, FL, USA and Gainesville, FL, USA?

RedCoach operates a bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Dr once daily. Tickets cost $60–90 and the journey takes 5h 10m.

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