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How to get fromSanibel to Jacksonvilleby bus (Flixbus), bus, train, car, taxi, or plane

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There are 7 ways to get from Sanibel to Jacksonville by bus (Flixbus), bus, train, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via University

    best
    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    8h 58m
    $137–185

  2. Drive  310.3 mi

    cheapest
    1. Drive from Sanibel to Jacksonvillecar car 310.3 mi
    6h
    $55–80

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Jacksonvilletrain train Floridian
    10h 44m
    $213–315

  4. Taxi to Ft. Myers, fly

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Jacksonville (JAX)plane plane RSW - JAX
    6h
    $163–578

  5. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    11h 3m
    $81–122

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane plane FLL - JAX
    6h 53m
    $200–476

  7. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    7h 31m
    $158–458

Ft. Myers (RSW) to Jacksonville (JAX) flights

Calendar72Weekly Planes
Duration4h 47mAverage Duration
Ticket$94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sanibel to Jacksonville.ExpandLaunch map view
  • Distance: 382.5 mi
  • Duration: 8h 58m

What companies run services between Sanibel, FL, USA and Jacksonville, FL, USA?

You can take a vehicle from Sanibel to Jacksonville via Fort Myers 7-11, University of South Florida, and Orlando Bus Station in around 8h 58m.

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