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How to get fromSanibel to Key Westby ferry, bus (Flixbus, Greyhound), car, taxi, plane, or bus

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There are 5 ways to get from Sanibel to Key West by ferry, bus (Flixbus, Greyhound), car, taxi, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry

    best
    1. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    4h 19m
    $167–174

  2. Drive 281.8 mi

    cheapest
    1. Drive from Sanibel to Key Westcar car 281.8 mi
    6h 7m
    $52–75

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 39m
    $70–117

  4. Taxi to Ft. Myers, fly

    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Key West International Airport (EYW)plane plane RSW - EYW
    5h 13m
    $560–907

  5. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    5h 35m
    $148–372

Ft. Myers (RSW) to Key West International Airport (EYW) flights

Calendar42Weekly Planes
Duration5h 43mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Sanibel to Key West.ExpandLaunch map view
  • Distance: 148.4 mi
  • Duration: 4h 19m

What companies run services between Sanibel, FL, USA and Key West, FL, USA?

Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a vehicle from Sanibel to N Roosevelt & 3rd Street via Mcgregor Blvd @ Davis Rd, South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 39m.

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