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How to get fromSanibel to Knoxvilleby taxi, plane, bus, train, bus (Flixbus), or car

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There are 6 ways to get from Sanibel to Knoxville by taxi, plane, bus, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Ft. Myers, fly

    best
    1. Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Mcghee Tyson Airport (TYS)plane plane RSW - TYS
    4h 55m
    $284–964

  2. Drive 771.6 mi

    cheapest
    1. Drive from Sanibel to Knoxvillecar car 771.6 mi
    13h 50m
    $141–204

  3. Taxi, bus, train

    1. Take the taxi from Sanibel to Fort Myers Amtrak Bus Stoptaxi taxi
    2. Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus bus
    3. Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    43h 16m
    $694–1,203

  4. Bus

    1. Take the bus from Fort Myers to Miamibus bus
    2. Take the bus from Miami to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d 1h
    $438–636

  5. Taxi to Punta Gorda Airport, fly

    1. Take the taxi from Sanibel to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Mcghee Tyson Airport (TYS)plane plane PGD - TYS
    3h 7m
    $303–872

  6. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus
    2. Take the train from Fort Lauderdale Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    45h 48m
    $664–1,180

Ft. Myers (RSW) to Mcghee Tyson Airport (TYS) flights

Calendar90Weekly Planes
Duration5h 14mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

Map of how to get from Sanibel to Knoxville.ExpandLaunch map view
  • Distance: 692.2 mi
  • Duration: 4h 55m

What companies run services between Sanibel, FL, USA and Knoxville, TN, USA?

You can take a vehicle from Sanibel to Knoxville Station Hall of Fame via Fort Myers, Miami, Washington Union Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 2d 1h.

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