There are 5 ways to get from Sanibel to Orlando by taxi, plane, bus (Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, fly
best- Take the taxi from Sanibel to Ft-Myers-Airport-RSWtaxi
- Fly from Ft. Myers (RSW) to Orlando (MCO)plane RSW - MCO
1h 57m$424–637Drive 170.9 mi
cheapest- Drive from Sanibel to Orlandocar 170.9 mi
3h 37m$32–45Bus via University
- Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus Miami
- Take the bus from University of South Florida to Orlando Bus Stationbus FlixBus 2421
5h 48m$114–149Bus, train
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus FlixBus 2421
- Take the train from Tampa to Orlandotrain Floridian
6h 56m$105–157Bus (Flixbus)
- Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus FlixBus 2421
7h 53m$54–82
Ft. Myers (RSW) to Orlando (MCO) flights
Comparing Your Travel Options
The cheapest way to get from Sanibel to Orlando is to drive which costs $30 - $45 and takes 3h 37m.
The fastest way to get from Sanibel to Orlando is to taxi and fly which takes 1h 57m and costs $420 - $650.
No, there is no direct bus from Sanibel to Orlando station. However, there are services departing from Fort Myers 7-11 and arriving at Orlando Bus Station via University of South Florida. The journey, including transfers, takes approximately 5h 48m.
The distance between Sanibel and Orlando is 166 miles. The road distance is 171.9 miles.
The best way to get from Sanibel to Orlando without a car is to bus via University which takes 5h 48m and costs $110 - $150.
It takes approximately 1h 57m to get from Sanibel to Orlando, including transfers.
Sanibel to Orlando bus services, operated by RedCoach, depart from Fort Myers 7-11 station.
Sanibel to Orlando bus services, operated by RedCoach, arrive at University of South Florida - 3801 USF Holly Dr station.
Yes, the driving distance between Sanibel to Orlando is 172 miles. It takes approximately 3h 37m to drive from Sanibel to Orlando.
There are 1940+ hotels available in Orlando.
What companies run services between Sanibel, FL, USA and Orlando, FL, USA?
You can take a vehicle from Sanibel to Orlando Bus Station via Fort Myers 7-11 and University of South Florida in around 5h 48m.
- Website
- southwest.com
Flights from Ft. Myers to Orlando
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- $45–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Orlando
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $23–55
- Website
- Amtrak
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- RedCoach
Want to know more about travelling around United States
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