There are 11 ways to get from Sansepolcro to Palermo by bus, train, plane, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train to Florence Peretola Airport, fly
best- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
6h 24m€47–231Bus, train to Bologna Guglielmo Marconi Airport, fly
cheapest- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane BLQ - PMO
7h 8m€37–179Bus, train, ferry
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
13h 47mBus via Rome
- Take the bus from Porta Del Ponte - Sansepolcro to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus Autoservizi Salemi S201
16h 45m€59–82Drive, car ferry
- Drive from Sansepolcro to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
16h 48m€99–142Bus to Forlì International Airport, fly
- Take the bus from Porta Del Ponte - Sansepolcro to Forlìbus
- Fly from Forlì International Airport (FRL) to Palermo Airport (PMO)plane FRL - PMO
5h 11m€154–439Bus, train, train to Pisa International Airport, fly
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
7h 33m€64–269Bus, train to Fiumicino International Airport, fly
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane FCO - PMO
6h 51m€50–185Bus, train via Casoria
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Palermo Centraletrain Ic
15h 11m€128–229Bus, train
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the train from Arezzo to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 15m€121–226Bus
- Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus
- Take the bus from Arezzo Terminal to Le Lupebus 138
- Take the bus from Siena to Palermobus
20h 23m€108–172
Florence Peretola Airport (FLR) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Sansepolcro to Palermo is to bus via Rome which costs €55 - €85 and takes 16h 45m.
The fastest way to get from Sansepolcro to Palermo is to bus and fly which takes 5h 11m and costs €150 - €440.
No, there is no direct bus from Sansepolcro to Palermo. However, there are services departing from Porta Del Ponte - Sansepolcro and arriving at Palermo Terminal Bus via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 16h 45m.
The distance between Sansepolcro and Palermo is 810 km.
The best way to get from Sansepolcro to Palermo without a car is to bus and train and ferry which takes 13h 47m and costs .
It takes approximately 6h 24m to get from Sansepolcro to Palermo, including transfers.
Sansepolcro to Palermo bus services, operated by Sulga Autolinee, depart from Porta Del Ponte - Sansepolcro station.
Sansepolcro to Palermo bus services, operated by Sulga Autolinee, arrive at Roma, Autostazione Tiburtina station.
There are 6010+ hotels available in Palermo.
What companies run services between Sansepolcro, Italy and Palermo, Italy?
You can take a bus from Porta Del Ponte - Sansepolcro to Palermo Terminal Bus via Roma, Autostazione Tiburtina in around 16h 45m.
- Website
- ryanair.com
Flights from Forlì International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €29–160
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Pisa International Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 20m
- When
- Sunday
- Estimated price
- €35–200
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 30m
- When
- Friday, Sunday, Monday, Thursday, Saturday, and Tuesday
- Estimated price
- €29–110
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €18–95
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €65–150
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €45–250
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €18–120
Flights from Florence Peretola Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Fiumicino International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €65–150
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €45–250
- Website
- flyulendo.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €22–70
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €11–110
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €18–95
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €17–120
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 1h 30m
- Frequency
- Every 20 minutes
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 1h 30m
- Frequency
- Every 20 minutes
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Arezzo to Bologna Centrale
- Ave. Duration
- 2h 31m
- Frequency
- Twice a week
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Arezzo to Roma Termini
- Ave. Duration
- 2h 48m
- Frequency
- 3 times a day
- Estimated price
- €23–35
- Website
- Trenitalia
Train from Arezzo to Roma Termini
- Ave. Duration
- 2h 48m
- Frequency
- 3 times a day
- Estimated price
- €23–35
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 33 min
- Frequency
- Twice daily
- Estimated price
- €12–20
- Website
- Trenitalia Frecce
Train from Arezzo to Napoli Afragola
- Ave. Duration
- 2h 32m
- Frequency
- Twice daily
- Estimated price
- €55–95
- Website
- Trenitalia Frecce
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 1m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 33 min
- Frequency
- Twice daily
- Estimated price
- €12–20
- Website
- Trenitalia Frecce
Train from Arezzo to Bologna Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
Train from Arezzo to Roma Termini
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- €27–50
- Website
- Trenitalia Frecce
Train from Arezzo to Napoli Afragola
- Ave. Duration
- 2h 32m
- Frequency
- Twice daily
- Estimated price
- €55–95
- Website
- Trenitalia Frecce
Train from Arezzo to Roma Termini
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- €27–50
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 36 min
- Frequency
- 4 times a day
- Estimated price
- €9–17
- Website
- Trenitalia Intercity
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 54m
- Frequency
- Twice a week
- Estimated price
- €45–85
- Website
- Trenitalia Intercity
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- €24–45
- Website
- Trenitalia Intercity
Train from Arezzo to Firenze S.M.N.
- Ave. Duration
- 36 min
- Frequency
- 4 times a day
- Estimated price
- €9–17
- Website
- Trenitalia Intercity
Train from Arezzo to Bologna Centrale
- Ave. Duration
- 1h 41m
- Frequency
- Every 2 hours
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Arezzo to Roma Termini
- Ave. Duration
- 3h 8m
- Frequency
- Every 4 hours
- Estimated price
- €22–40
- Website
- Trenitalia Intercity
Train from Napoli Afragola to Palermo Centrale
- Ave. Duration
- 9h 38m
- Frequency
- Twice a week
- Estimated price
- €70–130
- Website
- Trenitalia Intercity
Train from Arezzo to Roma Termini
- Ave. Duration
- 3h 8m
- Frequency
- Every 4 hours
- Estimated price
- €22–40
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 5h 37m
- Frequency
- Once daily
- Estimated price
- €45–80
- Website
- Italo Treno
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Sansepolcro Via Marconi to Arezzo Terminal
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €3–4
- Schedules at
- at-bus.it
Bus from Arezzo Terminal to Le Lupe
- Ave. Duration
- 1h 14m
- Frequency
- Every 4 hours
- Estimated price
- €4–6
- Schedules at
- at-bus.it
- Phone
- +39 075 5009641
- [email protected]
- Website
- sulga.it
Bus from Porta Del Ponte - Sansepolcro to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h
- Frequency
- 6 times a week
- Estimated price
- €23–27
- Schedules at
- sulga.it
- 2nd Class
- €23–27
Bus from Porta Del Ponte - Sansepolcro to Forlì
- Ave. Duration
- 1h 50m
- Frequency
- 6 times a week
- Estimated price
- €21–24
- Schedules at
- sulga.it
- 2nd Class
- €21–24
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus
- Ave. Duration
- 11h 45m
- Frequency
- Twice daily
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Palermo
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
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