There are 8 ways to get from Santa Ana to Puerto Barrios by bus, car, shuttle, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, drive via Chiquimula
best- Take the bus from Santa Ana to Metapánbus 235
- Drive from Metapán to Esquipulascar
- Take the bus from Esquipulas to Chiquimulabus
- Take the bus from Río Hondo to Puerto Barriosbus
8h 52mBus via Guatemala City
cheapest- Take the bus from Santa Ana to Guatemala Aguilar Batresbus Guatemala / ...
- Take the bus from Litegua Bus Station to Puerto Barriosbus Puerto Barrios-Morales-Ciudad Capital
10h 20m$21–41Drive 315.8 km
- Drive from Santa Ana to Puerto Barrioscar 315.8 km
5h 17m$39–55Shuttle to Cuscatlán International Airport, fly to Ramón Villeda Morales International Airport, drive
- Take a shuttle bus from Santa Ana to El Salvador International Airport
- Fly from Cuscatlán International Airport (SAL) to Ramón Villeda Morales International Airport (SAP)plane SAL - SAP
- Drive from Ramón Villeda Morales International Airport (SAP) to Puerto Barrioscar
5h 48m$482–855Bus, drive
- Take the bus from Santa Ana to Metapánbus 235
- Drive from Metapán to Esquipulascar
- Take the bus from Esquipulas to Zacapabus
- Take the bus from Río Hondo to Puerto Barriosbus
9h 1mBus
- Take the bus from Santa Ana to Estación Central 7a Avenida Zona 1bus San Salvador
- Take the bus from Litegua Bus Station to Puerto Barriosbus Puerto Barrios-Morales-Ciudad Capital
11h 5m$21–41Bus #2
- Take the bus from Gasolinera Puma Santa Maria, Santa Ana to Estación Central 7a Avenida Zona 1bus Estación Central 7a Avenida Zona 1 – Terminal San Carlos / ...
- Take the bus from Guatemala City to Puerto Barriosbus Gtm
11h 33m$33–57Bus to La Aurora International Airport, fly to Puerto Barrios Airport
- Take the bus from Santa Ana to Guatemalabus
- Fly from La Aurora International Airport (GUA) to Puerto Barrios Airport (PBR)plane GUA - PBR
7h 22m$180–224
Cuscatlán International Airport (SAL) to Ramón Villeda Morales International Airport (SAP) flights
Questions & Answers
The cheapest way to get from Santa Ana to Puerto Barrios is to bus which costs $30 - $60 and takes 11h 33m.
The fastest way to get from Santa Ana to Puerto Barrios is to drive which takes 5h 17m and costs $35 - $55.
No, there is no direct bus from Santa Ana to Puerto Barrios. However, there are services departing from Santa Ana and arriving at Puerto Barrios via Reformita and Litegua Bus Station. The journey, including transfers, takes approximately 10h 20m.
The distance between Santa Ana and Puerto Barrios is 359 km. The road distance is 315.8 km.
The best way to get from Santa Ana to Puerto Barrios without a car is to bus via Guatemala City which takes 10h 20m and costs $21 - $45.
It takes approximately 8h 52m to get from Santa Ana to Puerto Barrios, including transfers.
Santa Ana to Puerto Barrios bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), depart from Santa Ana station.
Santa Ana to Puerto Barrios bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), arrive at Guatemala Aguilar Batres station.
Yes, the driving distance between Santa Ana to Puerto Barrios is 316 km. It takes approximately 5h 17m to drive from Santa Ana to Puerto Barrios.
There are 38+ hotels available in Puerto Barrios.
What companies run services between Santa Ana, El Salvador and Puerto Barrios, Guatemala?
You can take a bus from Santa Ana to Puerto Barrios via Guatemala Aguilar Batres, Reformita, Plaza Barrios, and Litegua Bus Station in around 10h 20m.
- Website
- avianca.com
Flights from Cuscatlán International Airport to Ramón Villeda Morales International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $240–600
- Website
- tag.com.gt
Flights from La Aurora International Airport to Puerto Barrios Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Thursday, Wednesday, Friday, and Sunday
- Estimated price
- $130–170
Bus from Santa Ana to Metapán
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $1
Bus from Santa Ana to Metapán
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $1
- Phone
- +502 2326 3200
- [email protected]
- Website
- Rutas Orientales
Bus from Esquipulas to Chiquimula
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Schedules at
- Rutas Orientales
Bus from Esquipulas to Zacapa
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Schedules at
- Rutas Orientales
- Phone
- +502 2326 959
- [email protected]
- Website
- Litegua
Bus from Río Hondo to Puerto Barrios
- Ave. Duration
- 2h 52m
- Frequency
- Hourly
- Estimated price
- $7–20
- Schedules at
- Litegua
- Primera Plus
- $14
- Primera Clase
- $20
- Especial Plus
- $7
Bus from Río Hondo to Puerto Barrios
- Ave. Duration
- 2h 52m
- Frequency
- Hourly
- Estimated price
- $7–20
- Schedules at
- Litegua
- Primera Plus
- $14
- Primera Clase
- $20
- Especial Plus
- $7
Bus from Litegua Bus Station to Puerto Barrios
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $7–20
- Schedules at
- Litegua
- Primera Plus
- $14
- Primera Clase
- $20
- Especial Plus
- $7
Bus from Litegua Bus Station to Puerto Barrios
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $7–20
- Schedules at
- Litegua
- Primera Plus
- $14
- Primera Clase
- $20
- Especial Plus
- $7
- Phone
- +503 7491 3696
- [email protected]
- Website
- Alfarito Tours
Shuttle from Santa Ana to El Salvador International Airport
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $220
- Website
- Alfarito Tours
Bus from Santa Ana to Guatemala Aguilar Batres
- Ave. Duration
- 4h 5m
- Frequency
- 4 times a day
- Estimated price
- $14–20
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $14–20
Bus from Santa Ana to Estación Central 7a Avenida Zona 1
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $15–21
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $15–21
- Phone
- +52 962 625 2435
- [email protected]
- Website
- Tica Bus
Bus from Gasolinera Puma Santa Maria, Santa Ana to Estación Central 7a Avenida Zona 1
- Ave. Duration
- 4h 16m
- Frequency
- 3 times a day
- Estimated price
- $16–23
- Website
- Tica Bus
- Phone
- +502 2471 0952
- Website
- mmcorporacion.com
Bus from Guatemala City to Puerto Barrios
- Ave. Duration
- 6h
- Frequency
- 3 times a day
- Estimated price
- $16–35
- Schedules at
- mmcorporacion.com
- Phone
- +503 7841 5688
- [email protected]
- Website
- Transporte del SOL
Bus from Santa Ana to Guatemala
- Ave. Duration
- 3h 47m
- Frequency
- 3 times a day
- Estimated price
- $33
- Schedules at
- Transporte del SOL
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to plan an amazing trip around Scandinavia, Heading to Europe? Read this before you buy a Eurail Pass, and Italian Lakes: Getting around by train - to help you get the most out of your next trip.







