There are 6 ways to get from Santa Ana to Mexicali by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Santa Ana to Mexicalibus Plus / ...
7h 17m$700–1,900Drive 523.7 km
- Drive from Santa Ana to Mexicalicar 523.7 km
6h 47m$928–1,340Bus, fly to General Rodolfo Sánchez Taboada International Airport
- Take the bus from Santa Ana to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to General Rodolfo Sánchez Taboada International Airport (MXL)plane HMO - MXL
4h 35m$3,553–8,002Bus via Puerto Peñasco
- Take the bus from Santa Ana to Altarbus
- Take the bus from Altar to Puerto Peñascobus
- Take the bus from Puerto Peñasco to Mexicalibus
8h 28m$844–1,532Bus via Heroica Caborca
- Take the bus from Santa Ana to Caborcabus Plus / ...
- Take the bus from Caborca to Mexicalibus Tapachula
10h 37m$844–2,106Bus, fly to Tijuana International Airport
- Take the bus from Santa Ana to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to Tijuana International Airport (TIJ)plane HMO - TIJ
- Take the bus from Tijuana International Airport to Mexicalibus
7h 54m$2,653–5,552
Santa Ana to Mexicali by bus
Questions & Answers
The cheapest way to get from Santa Ana to Mexicali is to bus which costs $700 - $1900 and takes 7h 17m.
The fastest way to get from Santa Ana to Mexicali is to bus and fly which takes 4h 35m and costs $3500 - $8000.
Yes, there is a direct bus departing from Santa Ana and arriving at Mexicali. Services depart four times a day, and operate every day. The journey takes approximately 7h 17m.
The distance between Santa Ana and Mexicali is 521 km. The road distance is 523.7 km.
The best way to get from Santa Ana to Mexicali without a car is to bus which takes 7h 17m and costs $700 - $1900.
The bus from Santa Ana to Mexicali takes 7h 17m including transfers and departs four times a day.
Santa Ana to Mexicali bus services, operated by Tufesa Mexico, depart from Santa Ana station.
Santa Ana to Mexicali bus services, operated by Tufesa Mexico, arrive at Mexicali station.
Yes, the driving distance between Santa Ana to Mexicali is 524 km. It takes approximately 6h 47m to drive from Santa Ana to Mexicali.
Book your Santa Ana to Mexicali bus tickets online with Omio and 12go.asia.
What companies run services between Santa Ana, Sonora, Mexico and Mexicali, Mexico?
Tufesa Mexico operates a bus from Santa Ana to Mexicali hourly. Tickets cost $700–1,100 and the journey takes 7h 17m. Three other operators also service this route.
- Website
- volaris.com
Flights from Hermosillo International Airport to General Rodolfo Sánchez Taboada International Airport
- Ave. Duration
- 1h 13m
- When
- Tuesday and Thursday
- Estimated price
- $1,300–5,000
Flights from Hermosillo International Airport to Tijuana International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $1,400–3,600
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 17m
- Frequency
- Hourly
- Estimated price
- $700–1,100
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $700–1,000
- Titanium
- $750–1,100
Bus from Santa Ana to Caborca
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $140–380
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $140–380
- Titanium
- $150–370
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 52m
- Frequency
- 3 times a day
- Estimated price
- $950–1,400
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Puerto Peñasco to Mexicali
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $650–1,000
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Santa Ana to Caborca
- Ave. Duration
- 1h 18m
- Frequency
- 3 times a day
- Estimated price
- $340–550
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 50m
- Frequency
- 4 times a day
- Estimated price
- $900–1,900
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
Bus from Santa Ana to Caborca
- Ave. Duration
- 1h 41m
- Frequency
- Once daily
- Estimated price
- $330–480
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Santa Ana to Mexicali
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $850–1,200
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
Bus from Santa Ana to Hermosillo
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $700–1,000
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
Bus from Santa Ana to Hermosillo
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $700–1,000
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Santa Ana to Altar
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $110–170
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Altar to Puerto Peñasco
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- $180–270
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Puerto Peñasco to Mexicali
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a day
- Estimated price
- $550–1,100
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from Tijuana International Airport to Mexicali
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $350–650
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- futura.com.mx
Bus from Santa Ana to Caborca
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $320–460
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 713 120 0700
- [email protected]
- Website
- autotravel.mx
Bus from Caborca to Mexicali
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $700–1,600
- Schedules at
- autotravel.mx
- Book at
- autotravel.mx
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