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How to get fromSanta Ana to Ann Arborby plane, bus, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, or train

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There are 6 ways to get from Santa Ana to Ann Arbor by plane, bus, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County, bus

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Detroit (DTW)plane plane SNA - DTW
    2. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    6h 35m
    $337–4,553

  2. Train to Los Angeles International Airport, fly, bus

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Detroit (DTW)plane plane LAX - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    9h 18m
    $197–606

  3. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to Ann Arbor Amtrak Stationtrain train Wolverine
    2d 1h
    $782–1,669

  4. Bus

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Union Station to Ann Arbor Amtrak Stationbus bus
    2d 6h
    $455–818

  5. Drive 2,234.3 mi

    1. Drive from Santa Ana to Ann Arborcar car 2,234.3 mi
    35h 13m
    $408–589

  6. Train to San Diego International Airport, fly, bus

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Detroit (DTW)plane plane SAN - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    9h 46m
    $238–438

Santa Ana to Ann Arbor by train (Amtrak)

Calendar7Weekly Trains
Duration2d 1hAverage Duration
Ticket$782Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Ann Arbor.ExpandLaunch map view
  • Distance: 1,995 mi
  • Duration: 6h 35m

What companies run services between Santa Ana, CA, USA and Ann Arbor, MI, USA?

You can take a train from Santa Ana to Ann Arbor Amtrak Station via Fullerton Amtrak Station and Chicago Union Station in around 2d 1h. Alternatively, you can take a bus from Santa Ana to Ann Arbor Amtrak Station via Los Angeles Union Station, St Louis Bus Station, Chicago Bus Station, and Chicago Union Station in around 2d 6h.

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