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How to get fromSanta Ana to Antigua Guatemalaby plane, bus, car, train, or bus (Greyhound)

Find Transport to Antigua Guatemala

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There are 9 ways to get from Santa Ana to Antigua Guatemala by plane, bus, car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to La Aurora International Airport (GUA)plane plane SNA - GUA
    9h 32m
    $221–784

  2. Train to Los Angeles International Airport, fly

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to La Aurora International Airport (GUA)plane plane LAX - GUA
    10h 33m
    $181–567

  3. Bus

    1. Take the bus from Santa Ana to Cross Border Express, San Diegobus bus
    2. Take the bus from Tijuana International Airport to Tecatebus bus
    3. Take the bus from Tecate to México Politécnicobus bus
    4. Take the bus from Politécnico to Comitánbus bus
    5. Take the bus from Comitán to Antigua Guatemalabus bus
    2d 16h
    $227–321

  4. Drive 4,182.4 km

    1. Drive from Santa Ana to Antigua Guatemalacar car 4,182.4 km
    2d 1h
    $505–729

  5. Train to San Diego International Airport, fly

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to La Aurora International Airport (GUA)plane plane SAN - GUA
    13h 49m
    $242–659

  6. Bus via San Cristóbal de las Casas

    1. Take the bus from Santa Ana to Cross Border Express, San Diegobus bus
    2. Take the bus from Tijuana International Airport to Tecatebus bus
    3. Take the bus from Tecate to México Politécnicobus bus
    4. Take the bus from Terminal Central de Autobuses del Norte to San Cristóbal de las Casasbus bus
    5. Take the bus from San Cristóbal de las Casas to Antigua Guatemalabus bus
    2d 19h
    $269–416

  7. Train, bus via San Antonio

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Antonio Stationtrain train
    3. Take the bus from San Antonio to Terminal Central de Autobuses del Nortebus bus
    4. Take the bus from Politécnico to Comitánbus bus
    5. Take the bus from Comitán to Antigua Guatemalabus bus
    3d
    $702–1,330

  8. Bus #2

    1. Take the bus from Santa Ana to Tijuana - Plaza El Mexicanobus bus
    2. Take the bus from Tijuana Los Pinos to Huixtlabus bus
    3. Take the bus from Huixtla to Tapachulabus bus
    4. Take the bus from Tapachula to Antigua Guatemalabus bus
    3d 12h
    $230–330

  9. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the bus from Los Angeles to Guatemala Citybus bus
    3d 17h
    $313–426

John Wayne Airport Orange County (SNA) to La Aurora International Airport (GUA) flights

Calendar14Weekly Planes
Duration8h 30mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Antigua Guatemala.ExpandLaunch map view
  • Distance: 3,521.4 km
  • Duration: 9h 32m

What companies run services between Santa Ana, CA, USA and Antigua Guatemala?

United Airlines flies from John Wayne Airport Orange County (SNA) to La Aurora International Airport (GUA) twice daily. Alternatively, you can take a bus from Santa Ana to Antigua Guatemala via Cross Border Express, San Diego, Tijuana International Airport, Tecate, México Politécnico, Politécnico, and Comitán in around 2d 16h.

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Want to know more about travelling around Guatemala

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