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How to get fromSanta Ana to Columbusby plane, train, bus, bus (Greyhound), or car

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There are 6 ways to get from Santa Ana to Columbus by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to John Glenn Columbus International Airport (CMH)plane plane SNA - CMH
    7h 28m
    $270–1,036

  2. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    2d 4h
    $762–1,604

  3. Bus (Greyhound)

    1. Take the bus from Santa Ana Bus Stop to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    2d 5h
    $347–694

  4. Drive 2,222 mi

    1. Drive from Santa Ana to Columbuscar car 2,222 mi
    35h 43m
    $406–586

  5. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to John Glenn Columbus International Airport (CMH)plane plane LAX - CMH
    8h 26m
    $310–1,239

  6. Train to San Diego International Airport, fly

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to John Glenn Columbus International Airport (CMH)plane plane SAN - CMH
    8h 41m
    $330–961

Santa Ana to Columbus by train, foot, and bus

Calendar7Weekly Services
Duration2d 4hAverage Duration
Ticket$762Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Columbus.ExpandLaunch map view
  • Distance: 1,988.2 mi
  • Duration: 7h 28m

What companies run services between Santa Ana, CA, USA and Columbus, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from John Wayne Airport Orange County (SNA) to John Glenn Columbus International Airport (CMH) every 3 hours. Alternatively, you can take a bus from Santa Ana Bus Stop to Columbus via Los Angeles Union Station and St Louis Bus Station in around 2d 5h.

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