There are 5 ways to get from Santa Ana to Downtown San Diego by bus (Greyhound), train (Amtrak), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via San Diego (Greyhound)
best- Take the bus from Santa Ana to San Diegobus Los Angeles
1h 59m$21–43Bus (Flixbus)
cheapest- Take the bus from Santa Ana Bus Stop to San Diegobus FlixBus 2017
2h 15m$14–24Train via 11th Av & Broadway (Amtrak)
- Take the train from Santa Ana to San Diegotrain Pacific Surfliner
2h 24m$31–66Drive 88.8 mi
- Drive from Santa Ana to Downtown San Diegocar 88.8 mi
1h 33m$17–24Train (Amtrak)
- Take the train from Santa Ana to San Diegotrain Pacific Surfliner
2h 30m$29–65
Santa Ana to Downtown San Diego by bus, tram, and foot (Greyhound)
Questions & Answers
The cheapest way to get from Santa Ana to Downtown San Diego is to bus which costs $14 - $24 and takes 2h 15m.
The fastest way to get from Santa Ana to Downtown San Diego is to drive which takes 1h 33m and costs $16 - $24.
Yes, there is a direct bus departing from Santa Ana Bus Stop and arriving at San Diego. Services depart twice daily, and operate every day. The journey takes approximately 1h 45m.
Yes, there is a direct train departing from Santa Ana and arriving at San Diego. Services depart hourly, and operate every day. The journey takes approximately 2h 6m.
The distance between Santa Ana and Downtown San Diego is 92 miles. The road distance is 89.3 miles.
The best way to get from Santa Ana to Downtown San Diego without a car is to bus via San Diego which takes 1h 59m and costs $20 - $45.
It takes approximately 1h 59m to get from Santa Ana to Downtown San Diego, including transfers.
Santa Ana to Downtown San Diego bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Santa Ana to Downtown San Diego train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Santa Ana to Downtown San Diego is to bus via San Diego which takes 1h 59m and costs $20 - $45. Alternatively, you can train via 11th Av & Broadway, which costs $30 - $70 and takes 2h 24m.
What companies run services between Santa Ana, CA, USA and Downtown San Diego, CA, USA?
Greyhound Mexico operates a bus from Santa Ana to San Diego 3 times a day. Tickets cost $18–29 and the journey takes 1h 45m. Alternatively, Amtrak operates a train from Santa Ana to San Diego hourly. Tickets cost $29–65 and the journey takes 2h 6m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to San Diego
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- $29–65
- Website
- Amtrak
Train from Santa Ana to San Diego
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- $29–65
- Website
- Amtrak
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Santa Ana to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $18–29
- Schedules at
- Greyhound Mexico
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $14–24
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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More Questions & Answers
Santa Ana to Downtown San Diego bus services, operated by Greyhound Mexico, arrive at San Diego station.
Santa Ana to Downtown San Diego train services, operated by Amtrak, arrive at San Diego station.
Yes, the driving distance between Santa Ana to Downtown San Diego is 89 miles. It takes approximately 1h 33m to drive from Santa Ana to Downtown San Diego.
There are 1884+ hotels available in Downtown San Diego.












