Rome2Rio

How to get fromSanta Ana to Esquipulasby plane, bus, train, taxi, or car

Find Transport to Esquipulas

See all options

There are 7 ways to get from Santa Ana to Esquipulas by plane, bus, train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Cuscatlán International Airport, bus

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Cuscatlán International Airport (SAL)plane plane SNA - SAL
    2. Take the bus from San Salvador Airport to San Salvadorbus bus
    3. Take the bus from San Salvador to San Ignaciobus bus
    11h 23m
    $224–792

  2. Train to Los Angeles International Airport, fly to La Aurora International Airport, bus

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to La Aurora International Airport (GUA)plane plane LAX - GUA
    3. Take the bus from Guatemala to Esquipulasbus bus
    13h 3m
    $179–665

  3. Train, bus, taxi

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Marcos Amtraktrain train
    3. Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus bus
    4. Take the bus from Terminal Central de Autobuses del Norte to Huixtla ADObus bus
    5. Take the taxi from Huixtla to La Mesillataxi taxi
    6. Take the bus from La Mesilla to Calle Rooselvetbus bus
    7. Take the bus from Terminal de buses Oriente to San Luis Jilotepequebus bus
    8. Take the taxi from San Luis Jilotepeque to Esquipulastaxi taxi
    3d 16h

  4. Drive 4,367.5 km

    1. Drive from Santa Ana to Esquipulascar car 4,367.5 km
    2d 6h
    $527–761

  5. Fly John Wayne Airport Orange County to La Aurora International Airport, bus

    1. Fly from John Wayne Airport Orange County (SNA) to La Aurora International Airport (GUA)plane plane SNA - GUA
    2. Take the bus from Guatemala to Esquipulasbus bus
    12h 16m
    $201–715

  6. Train to Los Angeles International Airport, fly to Cuscatlán International Airport, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Cuscatlán International Airport (SAL)plane plane LAX - SAL
    3. Take the bus from San Salvador Airport to San Salvadorbus bus
    4. Take the bus from San Salvador to San Ignaciobus bus
    12h 31m
    $302–1,442

  7. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the bus from Los Angeles to Guatemala Citybus bus
    3. Take the bus from Guatemala to Esquipulasbus bus
    3d 17h
    $304–437

John Wayne Airport Orange County (SNA) to Cuscatlán International Airport (SAL) flights

Calendar33Weekly Planes
Duration8h 27mAverage Duration
Ticket$192Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santa Ana to Esquipulas.ExpandLaunch map view
  • Distance: 3,863.9 km
  • Duration: 11h 23m

What companies run services between Santa Ana, CA, USA and Esquipulas, Chiquimula, Guatemala?

There is no direct connection from Santa Ana to Esquipulas. However, you can take the taxi to Santa-Ana-Airport-SNA airport, fly to Cuscatlán International Airport (SAL), walk to San Salvador Airport, take the bus to San Salvador, take the bus to San Ignacio, drive to Nueva Ocotepeque, then take the bus to Esquipulas. Alternatively, you can take the train to Los Angeles, take the train to San Marcos Amtrak, walk to San Marcos, take the bus to Terminal Central de Autobuses del Norte, take the bus to Huixtla ADO, take the taxi to La Mesilla, take the bus to Calle Rooselvet, walk to Terminal de buses Oriente, take the bus to San Luis Jilotepeque, then take the taxi to Esquipulas.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around Guatemala

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides