There are 7 ways to get from Santa Ana to Gainesville by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Gainesville Regional Airport (GNV)plane SNA - GNV
7h 49m$160–635Train to Los Angeles International Airport, fly
cheapest- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Gainesville Regional Airport (GNV)plane LAX - GNV
10h 44m$128–494Bus
- Take the bus from Santa Ana to El Pasobus Cbx
- Take the bus from El Paso Bus Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to Tallahasseebus
- Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to University of Florida - 1956 Gale Lemerand Drbus
2d 5h$414–626Train, bus
- Take the train from Pomona Amtrak to Houstontrain
- Take the bus from Houston - Harrisburg Blvd to Ocalabus
- Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus
2d 9h$1,059–1,677Drive 2,345.7 mi
- Drive from Santa Ana to Gainesvillecar 2,345.7 mi
37h 58m$401–580Train, bus via Tallahassee
- Take the train from Santa Ana to Los Angelestrain
- Take the train from Los Angeles to Houstontrain
- Take the bus from Houston Bus Station to Tallahasseebus
- Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to University of Florida - 1956 Gale Lemerand Drbus
2d 10h$1,037–1,683Train, bus via Chicago
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Jacksonvilletrain
- Take the bus from Jacksonville to Gainesvillebus
3d 11h$2,069–3,329
Santa Ana to Gainesville by train and bus
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Gainesville is to train and fly which costs $120 - $500 and takes 10h 44m.
The fastest way to get from Santa Ana to Gainesville is to fly which takes 7h 49m and costs $160 - $650.
No, there is no direct bus from Santa Ana to Gainesville. However, there are services departing from Santa Ana and arriving at University of Florida - 1956 Gale Lemerand Dr via El Paso Bus Station, Houston Bus Station, C.K. Steele Plaza Gate 21 and Tallahassee - FSU - Old St Augustine at Intramural Field. The journey, including transfers, takes approximately 2 days 5h.
The distance between Santa Ana and Gainesville is 2125 miles. The road distance is 2359.4 miles.
The best way to get from Santa Ana to Gainesville without a car is to bus which takes 2 days 5h and costs $410 - $650.
It takes approximately 7h 49m to get from Santa Ana to Gainesville, including transfers.
Santa Ana to Gainesville bus services, operated by CBX Cross Border Express, depart from Santa Ana station.
The best way to get from Santa Ana to Gainesville is to fly which takes 7h 49m and costs $160 - $650. Alternatively, you can bus, which costs $410 - $650 and takes 2 days 5h.
Santa Ana to Gainesville bus services, operated by CBX Cross Border Express, arrive at El Paso station.
Gainesville is 3h ahead of Santa Ana. It is currently 7:31 PM in Santa Ana and 10:31 PM in Gainesville.
What companies run services between Santa Ana, CA, USA and Gainesville, FL, USA?
Delta and American Airlines fly from John Wayne Airport Orange County (SNA) to Gainesville Regional Airport (GNV) twice daily. Alternatively, you can take a bus from Santa Ana to University of Florida - 1956 Gale Lemerand Dr via El Paso, El Paso Bus Station, Houston Bus Station, C.K. Steele Plaza Gate 21, Varsity at Saint Agustine, and Tallahassee - FSU - Old St Augustine at Intramural Field in around 2d 5h.
- Website
- aa.com
Flights from John Wayne Airport Orange County to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 14m
- When
- Wednesday, Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 7h 51m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $150–650
Flights from Los Angeles International Airport to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $100–450
Flights from Los Angeles International Airport to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 8h 39m
- When
- Every day
- Estimated price
- $120–490
Flights from Los Angeles International Airport to Gainesville Regional Airport via Miami
- Ave. Duration
- 8h 58m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from John Wayne Airport Orange County to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 7h 16m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–600
Flights from Los Angeles International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $110–460
Flights from Los Angeles International Airport to Gainesville Regional Airport via Albuquerque, Atlanta
- Ave. Duration
- 9h 54m
- When
- Saturday
- Estimated price
- $110–460
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pomona Amtrak to Houston
- Ave. Duration
- 34h 29m
- Frequency
- 3 times a week
- Estimated price
- $850–1,400
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Los Angeles to Houston
- Ave. Duration
- 35h 10m
- Frequency
- 3 times a week
- Estimated price
- $850–1,400
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Chicago Union Station to Jacksonville
- Ave. Duration
- 34h 52m
- Frequency
- Once daily
- Estimated price
- $850–1,400
- Website
- Amtrak
- [email protected]
- Website
- Cross Border Xpress
Bus from Santa Ana to El Paso
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Website
- Cross Border Xpress
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from El Paso Bus Station to Houston Bus Station
- Ave. Duration
- 14h 45m
- Frequency
- Once daily
- Estimated price
- $130–210
- Website
- Greyhound
Bus from Houston Bus Station to Tallahassee
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Houston Bus Station to Tallahassee
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- $130–200
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Tallahassee - FSU - Old St Augustine at Intramural Field to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $35–50
- Website
- RedCoach
Bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $11–16
- Website
- RedCoach
Bus from Tallahassee - FSU - Old St Augustine at Intramural Field to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $35–50
- Website
- RedCoach
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Ocala
- Ave. Duration
- 15h 44m
- Frequency
- Once daily
- Estimated price
- $140–180
- Schedules at
- Omnibus Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $11–17
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Santa Ana to Gainesville is 2359 miles. It takes approximately 37h 58m to drive from Santa Ana to Gainesville.
There are 272+ hotels available in Gainesville.














