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How to get fromSanta Ana to Guadalajaraby plane, bus, car, or train

Find Transport to Guadalajara

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There are 8 ways to get from Santa Ana to Guadalajara by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane SNA - GDL
    5h 51m
    $1,939–7,231

  2. Bus

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Terminal Portalesbus bus
    32h 12m
    $3,006–3,242

  3. Drive  2,366.3 km

    1. Drive from Santa Ana to Guadalajaracar car 2,366.3 km
    26h 57m
    $4,964–7,170

  4. Bus to Tijuana International Airport, fly

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane TIJ - GDL
    8h 3m
    $2,222–5,055

  5. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane LAX - GDL
    7h 51m
    $2,425–5,615

  6. Bus via Tijuana

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Guadalajara Central ACNbus bus
    35h 49m
    $2,106–3,642

  7. Bus #2

    1. Take the bus from Santa Ana to Huntington Parkbus bus Lxus 3126 / ...
    2. Take the bus from Huntington Park to Zapopanbus bus Sacramento
    38h 10m
    $3,679–6,673

  8. Train, bus

    1. Take the train from Santa Ana to San Diegotrain train Pacific Surfliner
    2. Take the bus from Tijuana to Nueva Central Camionera de Guadalajara Mod 7bus bus
    39h 27m
    $4,179–7,784

Santa Ana to Guadalajara by bus

Calendar3Weekly Buses
Duration38h 10mAverage Duration
Ticket$3,679Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santa Ana to Guadalajara.ExpandLaunch map view
  • Distance: 2,072.2 km
  • Duration: 5h 51m

What companies run services between Santa Ana, CA, USA and Guadalajara, Mexico?

American Airlines, Frontier Airlines, and six other airlines fly from John Wayne Airport Orange County (SNA) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) 5 times a day. Alternatively, you can take a bus from Santa Ana to Sala 2 de la Central de Autobuses via Tijuana, Terminal Portales, and Carlos Salgado in around 32h 12m.

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