Rome2Rio

How to get fromSanta Ana to Guadalajaraby bus, plane, car, train, or shuttle

Find Transport to Guadalajara

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 10 ways to get from Santa Ana to Guadalajara by bus, plane, car, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tijuana International Airport, fly to Miguel Hidalgo Y Costilla Guadalajara International Airport

    best
    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane TIJ - GDL
    8h 4m
    $2,226–5,161

  2. Fly John Wayne Airport Orange County to Miguel Hidalgo Y Costilla Guadalajara International Airport

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane SNA - GDL
    8h 37m
    $1,567–7,167

  3. Bus

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Terminal Portalesbus bus
    32h 12m
    $3,010–3,248

  4. Drive  2,366.3 km

    1. Drive from Santa Ana to Guadalajaracar car 2,366.3 km
    27h 2m
    $6,031–8,711

  5. Train to Los Angeles International Airport, fly to Miguel Hidalgo Y Costilla Guadalajara International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane LAX - GDL
    7h 53m
    $2,426–5,415

  6. Train, train to Ontario International Airport, fly to Miguel Hidalgo Y Costilla Guadalajara International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL)plane plane ONT - GDL
    9h 7m
    $2,404–8,813

  7. Bus to Tijuana International Airport, fly to Lic. Jesús Terán Peredo International Airport, shuttle

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Lic. Jesús Terán Peredo International Airport (AGU)plane plane TIJ - AGU
    3. Take a shuttle bus from Aguascalientes to Nueva Central Camionera de Guadalajara Mod 7shuttle bus
    10h 54m
    $4,191–9,151

  8. Bus via Tijuana

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Guadalajara Central ACNbus bus
    35h 49m
    $2,110–3,648

  9. Bus #2

    1. Take the bus from Santa Ana to Huntington Parkbus bus Lxus 3126 / ...
    2. Take the bus from Huntington Park to Zapopanbus bus Sacramento
    38h 10m
    $3,681–6,678

  10. Train, bus

    1. Take the train from Santa Ana to San Diegotrain train Pacific Surfliner
    2. Take the bus from Tijuana to Nueva Central Camionera de Guadalajara Mod 7bus bus
    39h 27m
    $4,179–7,785

Santa Ana to Guadalajara by bus

Calendar3Weekly Buses
Duration38h 10mAverage Duration
Ticket$3,681Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Santa Ana to Guadalajara.ExpandLaunch map view
  • Distance: 2,102.2 km
  • Duration: 8h 4m

What companies run services between Santa Ana, CA, USA and Guadalajara, Mexico?

You can take a bus from Santa Ana to Sala 2 de la Central de Autobuses via Tijuana, Terminal Portales, and Carlos Salgado in around 32h 12m. Alternatively, Aeroméxico, Frontier Airlines, and four other airlines fly from John Wayne Airport Orange County (SNA) to Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) 5 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around Mexico

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Booking & Getting There