There are 6 ways to get from Santa Ana to Guaymas by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly John Wayne Airport Orange County to Hermosillo International Airport, bus
best- Fly from John Wayne Airport Orange County (SNA) to Hermosillo International Airport (HMO)plane SNA - HMO
- Take the bus from Hermosillo to Guaymasbus
6h 24m$2,117–9,059Bus via Ensenada
cheapest- Take the bus from Santa Ana to Ensenadabus Lxus 3103
- Take the bus from Ensenada to Empalmebus
26h 7m$2,028–3,276Bus
- Take the bus from Santa Ana to Huntington Parkbus Lxus 3126 / ...
- Take the bus from Huntington Park to Guaymasbus San José
18h 50m$2,167–3,960Drive 1,154.8 km
- Drive from Santa Ana to Guaymascar 1,154.8 km
13h 45m$2,413–3,485Bus to Tijuana International Airport, fly to Hermosillo International Airport, bus
- Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus
- Fly from Tijuana International Airport (TIJ) to Hermosillo International Airport (HMO)plane TIJ - HMO
- Take the bus from Hermosillo to Guaymasbus
8h 12m$2,699–6,582Bus to Tijuana International Airport, fly to Ciudad Obregón International Airport, bus
- Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus
- Fly from Tijuana International Airport (TIJ) to Ciudad Obregón International Airport (CEN)plane TIJ - CEN
- Take the bus from Ciudad Obregón to Guaymasbus
8h 48m$2,729–5,442
Santa Ana to Guaymas by bus
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Guaymas is to bus via Ensenada which costs $2000 - $3300 and takes 26h 7m.
The fastest way to get from Santa Ana to Guaymas is to fly and bus which takes 6h 24m and costs $2100 - $9500.
No, there is no direct bus from Santa Ana to Guaymas. However, there are services departing from Santa Ana and arriving at Guaymas via Huntington Park. The journey, including transfers, takes approximately 18h 50m.
The distance between Santa Ana and Guaymas is 980 km. The road distance is 1154.8 km.
The best way to get from Santa Ana to Guaymas without a car is to bus which takes 18h 50m and costs $2100 - $4000.
It takes approximately 6h 24m to get from Santa Ana to Guaymas, including transfers.
Santa Ana to Guaymas bus services, operated by Limousine Express, depart from Santa Ana station.
Santa Ana to Guaymas bus services, operated by Limousine Express, arrive at Huntington Park station.
Yes, the driving distance between Santa Ana to Guaymas is 1155 km. It takes approximately 13h 45m to drive from Santa Ana to Guaymas.
There are 139+ hotels available in Guaymas.
What companies run services between Santa Ana, CA, USA and Guaymas, Mexico?
You can take a bus from Santa Ana to Guaymas via Huntington Park in around 18h 50m.
- Website
- aa.com
Flights from John Wayne Airport Orange County to Hermosillo International Airport via Phoenix
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $1,300–7,500
- Website
- volaris.com
Flights from Tijuana International Airport to Hermosillo International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $1,800–4,800
Flights from Tijuana International Airport to Ciudad Obregón International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $1,900–4,000
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- $180–420
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $180–420
- Titanium
- $200–420
Bus from Huntington Park to Guaymas
- Ave. Duration
- 16h 50m
- Frequency
- Every 4 hours
- Estimated price
- $1,800–3,231
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $1,800–2,500
- Titanium
- $1,950–2,050
Bus from Hermosillo to Guaymas
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- $180–420
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $180–420
- Titanium
- $200–420
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $170–410
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $170–410
- Titanium
- $180–400
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- Every 2 hours
- Estimated price
- $260–750
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- Every 2 hours
- Estimated price
- $260–750
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $260–700
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- futura.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- $410–600
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- $410–600
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $240–550
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $390–600
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $390–600
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $270–550
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Santa Ana to Huntington Park
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- $470–700
- Website
- Limousine Express
- One Way
- $470–700
Bus from Santa Ana to Tijuana Aeropuerto, B.C.
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $550–850
- Website
- Limousine Express
- One Way
- $550–850
Bus from Santa Ana to Tijuana Aeropuerto, B.C.
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $550–850
- Website
- Limousine Express
- One Way
- $550–850
Bus from Santa Ana to Ensenada
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $700–1,000
- Website
- Limousine Express
- One Way
- $700–1,000
- [email protected]
- Website
- CBX Cross Border Express
Bus from Santa Ana to Huntington Park
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $360–550
- Schedules at
- CBX Cross Border Express
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobusesaguacaliente.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $150–250
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
Bus from Ensenada to Empalme
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $1,300–1,900
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $260–550
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
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