There are 6 ways to get from Santa Ana to Henderson by plane, bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, line 217 bus
best- Fly from John Wayne Airport Orange County (SNA) to Harry Reid International Airport (LAS)plane SNA - LAS
- Take the bus from South Strip Transit Terminal to EB Lake Mead after Boulderbus
2h 43m$136–371Bus (Flixbus)
cheapest- Take the bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtownbus FlixBus 2030
9h 13m$46–76Train, bus
- Take the train from Santa Ana to San Bernardino - Downtowntrain IE-OC Line
- Take the bus from San Bernardino Downtown Transit Center to Las Vegas Stripbus FlixBus 2037
6h 49m$89–128Drive 263.9 mi
- Drive from Santa Ana to Hendersoncar 263.9 mi
4h 22m$49–70Train, bus via Bonneville Transit Center Bay 14
- Take the train from Santa Ana to San Bernardino - Downtowntrain IE-OC Line
- Take the bus from San Bernardino to Las Vegas, NVbus Los Angeles / ...
7h 58m$57–81Bus via San Bernardino
- Take the bus from Katella + Harbor to San Bernardinobus 200
- Take the bus from San Bernardino to SB Las Vegas at Fashion Show Mallbus Riverside to Las Vegas
10h 1m$56–60
Santa Ana to Henderson by train, foot, and bus
Questions & Answers
The cheapest way to get from Santa Ana to Henderson is to bus which costs $45 - $80 and takes 9h 13m.
The fastest way to get from Santa Ana to Henderson is to fly and line 217 bus which takes 2h 43m and costs $130 - $380.
No, there is no direct bus from Santa Ana to Henderson. However, there are services departing from Main-1St and arriving at SB Boulder before Lake Mead via Anaheim Regional Transportation Intermodal Center and Bonneville Transit Center Bay 14. The journey, including transfers, takes approximately 9h 13m.
The distance between Santa Ana and Henderson is 249 miles. The road distance is 265.4 miles.
The best way to get from Santa Ana to Henderson without a car is to train and bus which takes 6h 49m and costs $85 - $130.
It takes approximately 2h 43m to get from Santa Ana to Henderson, including transfers.
Santa Ana to Henderson bus services, operated by Flixbus USA, depart from Anaheim Regional Transportation Intermodal Center station.
Santa Ana to Henderson bus services, operated by Flixbus USA, arrive at Las Vegas Downtown station.
Yes, the driving distance between Santa Ana to Henderson is 265 miles. It takes approximately 4h 22m to drive from Santa Ana to Henderson.
Book your Santa Ana to Henderson bus tickets online with Omio.
What companies run services between Santa Ana, CA, USA and Henderson, NV, USA?
Flixbus USA operates a bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtown 6 times a week. Tickets cost $40–70 and the journey takes 6h 30m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $35–260
- Phone
- (800) 371-LINK (5465)
- Website
- Metrolink Trains
Train from Santa Ana to San Bernardino - Downtown
- Ave. Duration
- 1h 24m
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Website
- Metrolink Trains
Train from Santa Ana to San Bernardino - Downtown
- Ave. Duration
- 1h 24m
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Website
- Metrolink Trains
- Phone
- +1 702-228-7433
- Website
- RTC
Bus from South Strip Transit Terminal to EB Lake Mead after Boulder
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More Questions & Answers
There are 1305+ hotels available in Henderson.



