There are 6 ways to get from Santa Ana to Indianapolis by plane, bus (Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Indianapolis (IND)plane SNA - IND
6h 43m$200–835Train to San Diego International Airport, fly
cheapest- Take the train from Santa Ana to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to Indianapolis (IND)plane SAN - IND
8h 14m$134–274Bus (Greyhound)
- Take the bus from Anaheim Regional Transportation Intermodal Center to Montclair Transcenterbus
- Take the bus from Montclair Transcenter to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
2d$336–538Train (Amtrak)
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain Southwest Chief
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
2d 1h$552–1,429Drive 2,046.9 mi
- Drive from Santa Ana to Indianapoliscar 2,046.9 mi
32h 46m$374–540Train to Los Angeles International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Indianapolis (IND)plane LAX - IND
7h 55m$178–405
Santa Ana to Indianapolis by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Indianapolis is to train and fly which costs $130 - $280 and takes 8h 14m.
The fastest way to get from Santa Ana to Indianapolis is to fly which takes 6h 43m and costs $200 - $850.
No, there is no direct bus from Santa Ana to Indianapolis station. However, there are services departing from Main-1St and arriving at Indianapolis Union Station via Anaheim Regional Transportation Intermodal Center, Montclair Transcenter and St Louis Bus Station. The journey, including transfers, takes approximately 2 days 0h.
No, there is no direct train from Santa Ana to Indianapolis. However, there are services departing from Santa Ana and arriving at Indianapolis via Fullerton Amtrak Station and Chicago Union Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Santa Ana and Indianapolis is 1818 miles. The road distance is 2058.9 miles.
The best way to get from Santa Ana to Indianapolis without a car is to bus which takes 2 days 0h and costs $330 - $550.
It takes approximately 6h 43m to get from Santa Ana to Indianapolis, including transfers.
Santa Ana to Indianapolis bus services, operated by Greyhound USA, depart from Anaheim Regional Transportation Intermodal Center station.
Santa Ana to Indianapolis train services, operated by Amtrak, depart from Fullerton Amtrak Station.
The best way to get from Santa Ana to Indianapolis is to fly which takes 6h 43m and costs $200 - $850. Alternatively, you can bus, which costs $330 - $550 and takes 2 days 0h, you could also train, which costs $550 - $1,500 and takes 2 days 1h.
What companies run services between Santa Ana, CA, USA and Indianapolis, IN, USA?
Southwest Airlines, United Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Main-1St to Indianapolis Union Station via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Montclair Transcenter, and St Louis Bus Station in around 2d.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Indianapolis via Denver
- Ave. Duration
- 5h 57m
- When
- Saturday and Sunday
- Estimated price
- $180–800
Flights from John Wayne Airport Orange County to Indianapolis via Phoenix
- Ave. Duration
- 5h 45m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from John Wayne Airport Orange County to Indianapolis via Las Vegas
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–800
Flights from John Wayne Airport Orange County to Indianapolis via Austin
- Ave. Duration
- 7h 7m
- When
- Monday to Wednesday
- Estimated price
- $200–900
Flights from Los Angeles International Airport to Indianapolis via Denver
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $150–700
Flights from Los Angeles International Airport to Indianapolis via Kansas City
- Ave. Duration
- 6h 20m
- When
- Monday to Friday
- Estimated price
- $150–700
Flights from Los Angeles International Airport to Indianapolis via Dallas
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $160–750
Flights from San Diego International Airport to Indianapolis
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $140–650
Flights from San Diego International Airport to Indianapolis via Denver
- Ave. Duration
- 5h 50m
- When
- Saturday and Sunday
- Estimated price
- $150–700
Flights from San Diego International Airport to Indianapolis via Nashville
- Ave. Duration
- 5h 55m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $160–700
Flights from San Diego International Airport to Indianapolis via Austin
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $160–750
Flights from San Diego International Airport to Indianapolis via Dallas
- Ave. Duration
- 6h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $150–700
Flights from San Diego International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 7h 30m
- When
- Saturday and Sunday
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $500–1,300
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $45–120
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $8–21
- Website
- Amtrak
Train from Santa Ana to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- $21–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Anaheim Regional Transportation Intermodal Center to Montclair Transcenter
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $9–16
- Website
- Greyhound
Bus from Montclair Transcenter to St Louis Bus Station
- Ave. Duration
- 39h 5m
- Frequency
- Once daily
- Estimated price
- $290–460
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Santa Ana to Indianapolis bus services, operated by Greyhound USA, arrive at Montclair Transcenter station.
Indianapolis is 3h ahead of Santa Ana. It is currently 3:50 PM in Santa Ana and 6:50 PM in Indianapolis.
Santa Ana to Indianapolis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Santa Ana to Indianapolis is 2059 miles. It takes approximately 32h 46m to drive from Santa Ana to Indianapolis.
Book your Santa Ana to Indianapolis train tickets online with Omio.
Book your Santa Ana to Indianapolis bus tickets online with Omio.
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