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How to get fromSanta Ana to Mesaby plane, tram, train, bus, taxi, car, or bus (Flixbus)

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There are 8 ways to get from Santa Ana to Mesa by plane, tram, train, bus, taxi, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Phoenix, tram

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Phoenix (PHX)plane plane SNA - PHX
    2. Take the tram from 44th St/Washington to Mesa Dr/Main Sttram tram
    2h 20m
    $280–685

  2. Bus

    cheapest
    1. Take the bus from ABC Supermarket - Westminster, CA to Lee's Sandwiches - Chandler, AZbus bus Southern CA
    10h 29m
    $49–64

  3. Train, bus

    1. Take the train from Santa Ana to San Bernardino - Downtowntrain train IE-OC Line
    2. Take the bus from San Bernardino, CA to Phoenixbus bus La
    9h 4m
    $61–90

  4. Train, taxi (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Maricopa Amtraktrain train
    3. Take the taxi from Maricopa Amtrak to Mesataxi taxi
    10h 12m
    $226–413

  5. Drive 371.6 mi

    1. Drive from Santa Ana to Mesacar car 371.6 mi
    6h 5m
    $68–98

  6. Fly to Scottsdale Airport, tram

    1. Fly from John Wayne Airport Orange County (SNA) to Scottsdale Airport (SCF)plane plane SNA - SCF
    2. Take the tram from University Dr/Rural Rd to Mesa Dr/Main Sttram tram
    2h 52m
    $82–357

  7. Bus via 24th St/Jefferson

    1. Take the bus from Santa Ana to Phoenixbus bus Cbx
    10h 28m
    $67–93

  8. Bus via San Bernardino

    1. Take the bus from Katella + Harbor to San Bernardinobus bus 200
    2. Take the bus from San Bernardino Downtown Transit Center to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus FlixBus 2054
    10h 50m
    $55–94

Santa Ana to Mesa by train, foot, bus, and tram

Calendar24Weekly Services
Duration9h 4mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Mesa.ExpandLaunch map view
  • Distance: 356.2 mi
  • Duration: 2h 20m

What companies run services between Santa Ana, CA, USA and Mesa, AZ, USA?

CBX Cross Border Express operates a bus from Santa Ana to Phoenix twice daily. Tickets cost $65–95 and the journey takes 9h 30m.

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