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How to get fromSanta Ana to Mesaby plane, tram, train, taxi, bus, or car

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There are 11 ways to get from Santa Ana to Mesa by plane, tram, train, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Phoenix Scottsdale Municipal Apt, tram

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Phoenix Scottsdale Municipal Apt (SCF)plane plane SNA - SCF
    2. Take the tram from University Dr/Rural Rd to Center/Main Sttram tram
    3h 21m
    $51–306

  2. Bus

    cheapest
    1. Take the bus from ABC Supermarket - Westminster, CA to Lee's Sandwiches - Chandler, AZbus bus Southern CA
    10h 29m
    $49–64

  3. Train, taxi (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Maricopa Amtraktrain train
    3. Take the taxi from Maricopa Amtrak to Mesataxi taxi
    10h 12m
    $324–489

  4. Bus via 24th St/Jefferson

    1. Take the bus from Santa Ana to Phoenixbus bus Cbx
    10h 28m
    $67–93

  5. Drive  371.6 mi

    1. Drive from Santa Ana to Mesacar car 371.6 mi
    6h 5m
    $62–89

  6. Fly John Wayne Airport Orange County to Phoenix, tram

    1. Fly from John Wayne Airport Orange County (SNA) to Phoenix (PHX)plane plane SNA - PHX
    2. Take the tram from 44th St/Washington to Center/Main Sttram tram
    3h 48m
    $54–484

  7. Train to Los Angeles International Airport, fly to Phoenix

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Phoenix (PHX)plane plane LAX - PHX
    5h 6m
    $128–394

  8. Train, line 62 bus to Long Beach Airport, fly to Phoenix, tram

    1. Take the train from Santa Ana to Norwalk / Santa Fe Springstrain train
    2. Take the bus from Norwalk / Imperial to 226th / Norwalkbus bus
    3. Fly from Long Beach Airport (LGB) to Phoenix (PHX)plane plane LGB - PHX
    4. Take the tram from 44th St/Washington to Center/Main Sttram tram
    6h 12m
    $82–456

  9. Train to Burbank Bob Hope Airport, fly to Phoenix

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Burbank Bob Hope Airport (BUR) to Phoenix (PHX)plane plane BUR - PHX
    5h 54m
    $67–301

  10. Train, train to Ontario International Airport, fly to Phoenix

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Phoenix (PHX)plane plane ONT - PHX
    6h 23m
    $88–368

  11. Train, bus

    1. Take the train from Santa Ana to L.A. Union Stationtrain train OC Line
    2. Take the bus from Los Angeles Union Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus FlixBus 2054
    12h 48m
    $85–133

Santa Ana to Mesa by bus and tram

Calendar14Weekly Services
Duration10h 28mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santa Ana to Mesa.ExpandLaunch map view
  • Distance: 359.4 mi
  • Duration: 3h 21m

What companies run services between Santa Ana, CA, USA and Mesa, AZ, USA?

CBX Cross Border Express operates a bus from Santa Ana to Phoenix twice daily. Tickets cost $65–95 and the journey takes 9h 30m.

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