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How to get fromSanta Ana to Mexico Cityby plane, bus, train, or car

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There are 8 ways to get from Santa Ana to Mexico City by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Benito Juárez International Airport (MEX)plane plane SNA - MEX
    5h 32m
    $2,300–9,091

  2. Bus

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Terminal Central Del Sur - Taxqueñabus bus
    45h 5m
    $3,986–7,318

  3. Train, bus via San Antonio

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Antonio Stationtrain train
    3. Take the bus from San Antonio to Terminal Central de Autobuses del Nortebus bus
    2d 4h
    $8,680–19,292

  4. Drive  2,891 km

    1. Drive from Santa Ana to Mexico Citycar car 2,891 km
    33h 5m
    $5,963–8,613

  5. Bus to Tijuana International Airport, fly

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Benito Juárez International Airport (MEX)plane plane TIJ - MEX
    7h 41m
    $2,482–5,412

  6. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Benito Juárez International Airport (MEX)plane plane LAX - MEX
    7h 33m
    $2,986–7,108

  7. Bus via Tepotzotlán

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Tepotzotlánbus bus
    45h 52m
    $3,816–9,258

  8. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the bus from Los Angeles to Terminal Central de Autobuses del Nortebus bus
    2d 10h
    $3,686–4,603

Santa Ana to Mexico City by bus

Calendar35Weekly Buses
Duration45h 52mAverage Duration
Ticket$3,816Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santa Ana to Mexico City.ExpandLaunch map view
  • Distance: 2,449.9 km
  • Duration: 5h 32m

What companies run services between Santa Ana, CA, USA and Mexico City, Mexico?

Delta, Aeroméxico, and three other airlines fly from John Wayne Airport Orange County (SNA) to Benito Juárez International Airport (MEX) every 3 hours. Alternatively, you can take a bus from Santa Ana to Terminal Central Del Sur - Taxqueña via Tijuana in around 45h 5m.

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Want to know more about travelling around Mexico

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