Rome2Rio

How to get fromSanta Ana to Mexico Cityby bus, plane, train, or car

Find Transport to Mexico City

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 10 ways to get from Santa Ana to Mexico City by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tijuana International Airport, fly to Benito Juárez International Airport

    best
    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Benito Juárez International Airport (MEX)plane plane TIJ - MEX
    7h 25m
    $2,496–6,331

  2. Fly John Wayne Airport Orange County to Benito Juárez International Airport

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to Benito Juárez International Airport (MEX)plane plane SNA - MEX
    6h 23m
    $1,937–9,037

  3. Bus

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Terminal Central Del Sur - Taxqueñabus bus
    45h 5m
    $4,000–7,338

  4. Train, bus via San Antonio

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Antonio Stationtrain train
    3. Take the bus from San Antonio to Terminal Central de Autobuses del Nortebus bus
    2d 4h
    $16,981–27,470

  5. Drive  2,891 km

    1. Drive from Santa Ana to Mexico Citycar car 2,891 km
    33h 5m
    $7,368–10,642

  6. Train to Los Angeles International Airport, fly to Benito Juárez International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Benito Juárez International Airport (MEX)plane plane LAX - MEX
    7h 31m
    $3,296–5,385

  7. Bus to Tijuana International Airport, fly to Felipe Ángeles International Airport

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Felipe Ángeles International Airport (NLU)plane plane TIJ - NLU
    9h 14m
    $2,446–6,031

  8. Bus to Tijuana International Airport, fly to Licenciado Adolfo López Mateos International Airport

    1. Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus bus
    2. Fly from Tijuana International Airport (TIJ) to Licenciado Adolfo López Mateos International Airport (TLC)plane plane TIJ - TLC
    9h 29m
    $3,236–7,111

  9. Bus via Tepotzotlán

    1. Take the bus from Santa Ana to Tijuana Central, B.C.bus bus Lxus 3105 / ...
    2. Take the bus from Tijuana to Tepotzotlánbus bus
    45h 52m
    $3,830–9,278

  10. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the bus from Los Angeles to Terminal Central de Autobuses del Nortebus bus
    2d 10h
    $3,986–4,881

Santa Ana to Mexico City by bus

Calendar35Weekly Buses
Duration45h 52mAverage Duration
Ticket$3,830Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Santa Ana to Mexico City.ExpandLaunch map view
  • Distance: 2,485 km
  • Duration: 7h 25m

What companies run services between Santa Ana, CA, USA and Mexico City, Mexico?

You can take a bus from Santa Ana to Terminal Central Del Sur - Taxqueña via Tijuana in around 45h 5m. Alternatively, Aeroméxico, United Airlines, and American Airlines fly from John Wayne Airport Orange County (SNA) to Benito Juárez International Airport (MEX) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around Mexico

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Booking & Getting There