Rome2Rio

How to get fromSanta Ana to Mississippiby plane, bus (Greyhound), train, bus, car, or train (Amtrak)

Find Transport to Mississippi

See all options

There are 8 ways to get from Santa Ana to Mississippi by plane, bus (Greyhound), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Memphis

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Memphis (MEM)plane plane SNA - MEM
    5h 39m
    $310–810

  2. Fly John Wayne Airport Orange County to Gulfport-Biloxi Regional Airport

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to Gulfport-Biloxi Regional Airport (GPT)plane plane SNA - GPT
    6h 16m
    $149–597

  3. Bus (Greyhound)

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Jacksonbus bus
    41h 10m
    $344–522

  4. Train, bus

    1. Take the train from Pomona Amtrak to Longviewtrain train Texas Eagle
    2. Take the bus from Longview Bus Station to Jacksonbus bus Greyhound US0604
    2d 4h
    $1,053–1,688

  5. Drive  1,793.3 mi

    1. Drive from Santa Ana to Jacksoncar car 1,793.3 mi
    28h 48m
    $307–443

  6. Fly John Wayne Airport Orange County to Jackson/Vicksburg

    1. Fly from John Wayne Airport Orange County (SNA) to Jackson/Vicksburg (JAN)plane plane SNA - JAN
    6h
    $178–583

  7. Train to Los Angeles International Airport, fly to Memphis

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Memphis (MEM)plane plane LAX - MEM
    6h 39m
    $208–819

  8. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Jacksontrain train
    2d 4h
    $1,119–1,889

Santa Ana to Mississippi by bus (Greyhound)

Calendar14Weekly Buses
Duration41h 10mAverage Duration
Ticket$344Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Santa Ana to Mississippi.ExpandLaunch map view
  • Distance: 1,600.3 mi
  • Duration: 5h 39m

What companies run services between Santa Ana, CA, USA and Mississippi, USA?

Southwest Airlines, American Airlines, and three other airlines fly from John Wayne Airport Orange County (SNA) to Memphis (MEM) every 2 hours. Alternatively, you can take a bus from Santa Ana to Jackson via Los Angeles Union Station and Dallas Bus Station in around 41h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There