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How to get fromSanta Ana to Niagara Fallsby plane, train (Amtrak), bus (Greyhound), car, train, or bus

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There are 7 ways to get from Santa Ana to Niagara Falls by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Buffalo Niagara International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Buffalo Niagara International Airport (BUF)plane plane SNA - BUF
    9h 15m
    $285–1,063

  2. Train to Los Angeles International Airport, fly to Buffalo Niagara International Airport

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Buffalo Niagara International Airport (BUF)plane plane LAX - BUF
    11h 55m
    $244–474

  3. Train

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    2d 9h
    $756–1,879

  4. Bus

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    2d 15h
    $377–765

  5. Drive 2,510.7 mi

    1. Drive from Santa Ana to Niagara Fallscar car 2,510.7 mi
    40h 6m
    $459–662

  6. Train to Los Angeles International Airport, fly to Toronto Pearson International Airport, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Toronto Pearson International Airport (YYZ)plane plane LAX - YYZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    11h 34m
    $250–898

  7. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Union Station to Port Huron Stationbus bus
    3. Take the bus from Sarnia to Torontobus bus
    4. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    2d 12h
    $740–1,662

Santa Ana to Niagara Falls by train

Calendar7Weekly Trains
Duration2d 9hAverage Duration
Ticket$756Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Niagara Falls.ExpandLaunch map view
  • Distance: 2,233.7 mi
  • Duration: 9h 15m

What companies run services between Santa Ana, CA, USA and Niagara Falls, NY, USA?

United Airlines, Southwest Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a train from Santa Ana to Niagara Falls Amtrak Station via Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2d 9h.

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