There are 9 ways to get from Santa Ana to Niagara Falls by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly John Wayne Airport Orange County to Buffalo Niagara International Airport, bus
best- Fly from John Wayne Airport Orange County (SNA) to Buffalo Niagara International Airport (BUF)plane SNA - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
8h 17m$232–940Fly John Wayne Airport Orange County to Toronto Pearson International Airport, bus
cheapest- Fly from John Wayne Airport Orange County (SNA) to Toronto Pearson International Airport (YYZ)plane SNA - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
9h 6m$162–648Train
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain
2d 9h$755–2,119Bus
- Take the bus from Santa Ana to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Columbusbus
- Take the bus from Columbus to Buffalobus
2d 15h$428–682Drive 2,510.7 mi
- Drive from Santa Ana to Niagara Fallscar 2,510.7 mi
39h 56m$459–662Train to Los Angeles International Airport, fly to Buffalo Niagara International Airport, bus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Buffalo Niagara International Airport (BUF)plane LAX - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
9h 29m$241–454Train to Los Angeles International Airport, fly to Toronto Pearson International Airport, bus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Toronto Pearson International Airport (YYZ)plane LAX - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
11h 4m$191–902Fly Long Beach Airport to Buffalo Niagara International Airport, bus
- Fly from Long Beach Airport (LGB) to Buffalo Niagara International Airport (BUF)plane LGB - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
12h 7m$314–1,321Train, bus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Union Station to Port Huron Stationbus
- Take the bus from Sarnia to Torontobus
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
2d 12h$723–1,833
Santa Ana to Niagara Falls by train
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Niagara Falls is to train and fly and bus which costs $240 - $460 and takes 9h 29m.
The fastest way to get from Santa Ana to Niagara Falls is to fly and bus which takes 8h 17m and costs $230 - $950.
No, there is no direct bus from Santa Ana to Niagara Falls. However, there are services departing from Santa Ana and arriving at Main Street & Pine Avenue via Los Angeles Union Station, St Louis Bus Station, S Grant Ave & E Mound St, Columbus and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 2 days 15h.
No, there is no direct train from Santa Ana to Niagara Falls station. However, there are services departing from Santa Ana and arriving at Niagara Falls Amtrak Station via Fullerton Amtrak Station, Chicago Union Station and Buffalo Depew Station. The journey, including transfers, takes approximately 2 days 9h.
The distance between Santa Ana and Niagara Falls is 2243 miles. The road distance is 2525.4 miles.
The best way to get from Santa Ana to Niagara Falls without a car is to train which takes 2 days 9h and costs $750 - $2,200.
It takes approximately 8h 17m to get from Santa Ana to Niagara Falls, including transfers.
Santa Ana to Niagara Falls bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Santa Ana to Niagara Falls train services, operated by Amtrak, depart from Fullerton Amtrak Station.
The best way to get from Santa Ana to Niagara Falls is to train which takes 2 days 9h and costs $750 - $2,200. Alternatively, you can bus, which costs $420 - $700 and takes 2 days 15h.
What companies run services between Santa Ana, CA, USA and Niagara Falls, NY, USA?
You can take a train from Santa Ana to Niagara Falls Amtrak Station via Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2d 9h. Alternatively, you can take a bus from Santa Ana to Main Street & Pine Avenue via Los Angeles Union Station, St Louis Bus Station, Columbus, S Grant Ave & E Mound St, S High St & E Rich St, Columbus, Buffalo, and Ellicott Street & MTC Static in around 2d 15h.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Buffalo Niagara International Airport via Denver
- Ave. Duration
- 6h 50m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $200–900
Flights from Los Angeles International Airport to Buffalo Niagara International Airport via Denver
- Ave. Duration
- 6h 30m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 6h 47m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 6h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from Los Angeles International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 7h
- When
- Wednesday, Thursday, and Sunday
- Estimated price
- $200–850
Flights from Long Beach Airport to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $300–1,300
Flights from Long Beach Airport to Buffalo Niagara International Airport via Denver
- Ave. Duration
- 7h 45m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $300–1,300
Flights from Long Beach Airport to Buffalo Niagara International Airport via Las Vegas
- Ave. Duration
- 7h 30m
- When
- Monday, Friday, Tuesday, Wednesday, and Saturday
- Estimated price
- $300–1,300
Flights from Long Beach Airport to Buffalo Niagara International Airport via Phoenix
- Ave. Duration
- 8h 3m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $310–1,300
Flights from Long Beach Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 9h 35m
- When
- Sunday and Friday
- Estimated price
- $320–1,400
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $600–1,600
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–370
- Website
- Amtrak
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 3 times a day
- Estimated price
- $9–24
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $9–25
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $9–25
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $600–1,600
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Columbus to Buffalo
- Ave. Duration
- 6h 25m
- Frequency
- 6 times a week
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Sarnia to Toronto
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Santa Ana to Niagara Falls bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Niagara Falls is 3h ahead of Santa Ana. It is currently 10:41 PM in Santa Ana and 1:41 AM in Niagara Falls.
Santa Ana to Niagara Falls train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Santa Ana to Niagara Falls is 2525 miles. It takes approximately 39h 56m to drive from Santa Ana to Niagara Falls.
Book your Santa Ana to Niagara Falls train tickets online with Omio.
Book your Santa Ana to Niagara Falls bus tickets online with Omio.
There are 798+ hotels available in Niagara Falls.







