There are 3 ways to get from Santa Ana to Old Town San Diego by bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stopbus Greyhound US0831
1h 45m$12–25Train (Amtrak)
- Take the train from Santa Ana to San Diego Old Town Transportation Centertrain Pacific Surfliner
1h 51m$27–60Drive 85.5 mi
- Drive from Santa Ana to Old Town San Diegocar 85.5 mi
1h 31m$16–23
Santa Ana to Old Town San Diego by bus
Questions & Answers
The cheapest way to get from Santa Ana to Old Town San Diego is to bus which costs $12 - $25 and takes 1h 45m.
The fastest way to get from Santa Ana to Old Town San Diego is to drive which takes 1h 31m and costs $15 - $23.
Yes, there is a direct bus departing from Santa Ana Bus Stop and arriving at San Diego Greyhound Bus Stop. Services depart three times a day, and operate every day. The journey takes approximately 1h 45m.
Yes, there is a direct train departing from Santa Ana and arriving at San Diego Old Town Transportation Center. Services depart hourly, and operate every day. The journey takes approximately 1h 51m.
The distance between Santa Ana and Old Town San Diego is 87 miles. The road distance is 86 miles.
The best way to get from Santa Ana to Old Town San Diego without a car is to bus which takes 1h 45m and costs $12 - $25.
The bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop takes 1h 45m including transfers and departs three times a day.
Santa Ana to Old Town San Diego bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Santa Ana to Old Town San Diego train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Santa Ana to Old Town San Diego is to bus which takes 1h 45m and costs $12 - $25. Alternatively, you can train, which costs $27 - $60 and takes 1h 51m.
What companies run services between Santa Ana, CA, USA and Old Town San Diego, San Diego County, CA, USA?
Greyhound USA operates a bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop twice daily. Tickets cost $12–25 and the journey takes 1h 45m. Flixbus USA also services this route once daily. Alternatively, Amtrak operates a train from Santa Ana to San Diego Old Town Transportation Center hourly. Tickets cost $27–60 and the journey takes 1h 51m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- $27–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $12–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stop
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–22
- Schedules at
- Flixbus USA
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More Questions & Answers
Santa Ana to Old Town San Diego bus services, operated by Greyhound USA, arrive at San Diego Greyhound Bus Stop station.
Santa Ana to Old Town San Diego train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
Yes, the driving distance between Santa Ana to Old Town San Diego is 86 miles. It takes approximately 1h 31m to drive from Santa Ana to Old Town San Diego.
Book your Santa Ana to Old Town San Diego train tickets online with Omio.
Book your Santa Ana to Old Town San Diego bus tickets online with Omio and FlixBus.
There are 2063+ hotels available in Old Town San Diego.









