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How to get fromSanta Ana to Palo Altoby plane, train, bus (Greyhound), train (Amtrak), car, or bus

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There are 9 ways to get from Santa Ana to Palo Alto by plane, train, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Norman Y. Mineta San José International Airport, Caltrain

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    2. Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain train
    3h 59m
    $509–811

  2. Bus, line 22 bus

    cheapest
    1. Take the bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwichbus bus Westminster
    2. Take the bus from King & Tully to El Camino & Churchillbus bus 22
    10h 19m
    $49–67

  3. Bus (Greyhound)

    1. Take the bus from Santa Ana Bus Stop to San Jose Diridon Stationbus bus Greyhound US0831
    8h 51m
    $73–108

  4. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    12h 29m
    $254–396

  5. Drive  387.6 mi

    1. Drive from Santa Ana to Palo Altocar car 387.6 mi
    6h 33m
    $67–96

  6. Fly John Wayne Airport Orange County to San Francisco International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2. Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain train
    4h 4m
    $115–350

  7. Fly John Wayne Airport Orange County to Oakland International Airport, train

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    5h 37m
    $238–796

  8. Train, line 62 bus to Long Beach Airport, fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Take the train from Santa Ana to Norwalk / Santa Fe Springstrain train
    2. Take the bus from Norwalk / Imperial to 226th / Norwalkbus bus
    3. Fly from Long Beach Airport (LGB) to Norman Y. Mineta San José International Airport (SJC)plane plane LGB - SJC
    4. Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain train
    6h 8m
    $87–493

  9. Train, train to Ontario International Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Norman Y. Mineta San José International Airport (SJC)plane plane ONT - SJC
    6h 29m
    $348–825

Santa Ana to Palo Alto by bus and train (Greyhound)

Calendar7Weekly Services
Duration8h 51mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santa Ana to Palo Alto.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 3h 59m

What companies run services between Santa Ana, CA, USA and Palo Alto, CA, USA?

Greyhound USA operates a bus from Santa Ana Bus Stop to San Jose Diridon Station once daily. Tickets cost $65–110 and the journey takes 8h 10m. Alternatively, you can take a train from Santa Ana to California Avenue Caltrain Northbound via Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 12h 29m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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