There are 5 ways to get from Santa Ana to Panama City by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY)plane SNA - PTY
9h 24m$286–921Train to San Diego International Airport, fly
cheapest- Take the train from Santa Ana to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to Tocumen International Airport (PTY)plane SAN - PTY
11h 31m$257–846Train, bus
- Take the train from Santa Ana to Los Angelestrain
- Take the bus from Los Angeles to Managuabus
- Take the bus from Managua to Terminal NicaBusbus
- Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus
5d 9h$436–547Drive 6,042.8 km
- Drive from Santa Ana to Panama Citycar 6,042.8 km
3d 5h$827–1,195Train to Los Angeles International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Tocumen International Airport (PTY)plane LAX - PTY
11h 17m$456–674
John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from Santa Ana to Panama City is to train and fly which costs $250 - $850 and takes 11h 31m.
The fastest way to get from Santa Ana to Panama City is to fly which takes 9h 24m and costs $280 - $950.
The distance between Santa Ana and Panama City is 4820 km. The road distance is 6042.8 km.
The best way to get from Santa Ana to Panama City without a car is to train and bus which takes 5 days 9h and costs $430 - $550.
It takes approximately 9h 24m to get from Santa Ana to Panama City, including transfers.
Panama City is 2h ahead of Santa Ana. It is currently 11:10 AM in Santa Ana and 1:10 PM in Panama City.
Yes, the driving distance between Santa Ana to Panama City is 6043 km. It takes approximately 3 days 5h to drive from Santa Ana to Panama City.
There are 884+ hotels available in Panama City.
What companies run services between Santa Ana, CA, USA and Panama City, Panama?
United Airlines, Copa Airlines, and Southwest Airlines fly from John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY) 3 times a day.
- Website
- copaair.com
Flights from John Wayne Airport Orange County to Tocumen International Airport via Denver
- Ave. Duration
- 9h 48m
- When
- Sunday
- Estimated price
- $240–900
Flights from John Wayne Airport Orange County to Tocumen International Airport via Austin
- Ave. Duration
- 10h
- When
- Monday, Thursday, and Saturday
- Estimated price
- $220–850
Flights from John Wayne Airport Orange County to Tocumen International Airport via Las Vegas
- Ave. Duration
- 10h 10m
- When
- Thursday
- Estimated price
- $220–850
Flights from John Wayne Airport Orange County to Tocumen International Airport via San Jose Cabo
- Ave. Duration
- 10h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $220–850
Flights from Los Angeles International Airport to Tocumen International Airport
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $190–750
Flights from San Diego International Airport to Tocumen International Airport
- Ave. Duration
- 6h 22m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $190–750
- Website
- united.com
Flights from John Wayne Airport Orange County to Tocumen International Airport via Houston
- Ave. Duration
- 8h 24m
- When
- Every day
- Estimated price
- $220–850
Flights from John Wayne Airport Orange County to Tocumen International Airport via Denver
- Ave. Duration
- 9h 28m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $240–900
Flights from John Wayne Airport Orange County to Tocumen International Airport via Las Vegas
- Ave. Duration
- 10h 10m
- When
- Thursday
- Estimated price
- $220–850
Flights from Los Angeles International Airport to Tocumen International Airport
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $190–750
Flights from San Diego International Airport to Tocumen International Airport
- Ave. Duration
- 6h 22m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $190–750
Flights from San Diego International Airport to Tocumen International Airport via Houston
- Ave. Duration
- 8h 37m
- When
- Every day
- Estimated price
- $200–750
- Website
- avianca.com
Flights from Los Angeles International Airport to Tocumen International Airport via San Salvador
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $400–600
- Website
- aa.com
Flights from San Diego International Airport to Tocumen International Airport via Miami
- Ave. Duration
- 11h 54m
- When
- Every day
- Estimated price
- $220–850
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Santa Ana to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- $28–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 213 368 1172
- [email protected]
- Website
- busesusatours.com
Bus from Los Angeles to Managua
- Ave. Duration
- 4d 6h
- Frequency
- Once a week
- Estimated price
- $330–400
- Schedules at
- busesusatours.com
- Phone
- +505 2222 2276
- [email protected]
- Website
- nicabus.com.ni
Bus from Managua to Terminal NicaBus
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $37–38
- Website
- https://nicabus.com.ni/en/
- Phone
- +52 962 625 2435
- [email protected]
- Website
- ticabus.com
Bus from Terminal Tica Bus San José to Terminal Tica Bus Panamá
- Ave. Duration
- 16h 10m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- https://www.ticabus.com/en/
Want to know more about travelling around Panama
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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