There are 5 ways to get from Santa Ana to Panama City by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY)plane SNA - PTY
9h 37m$236–771Train to San Diego International Airport, fly
cheapest- Take the train from Santa Ana to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to Tocumen International Airport (PTY)plane SAN - PTY
11h 24m$200–690Train, bus
- Take the train from Santa Ana to Los Angelestrain
- Take the bus from Los Angeles to San Salvadorbus
- Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus
- Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus
5d 8h$417–571Drive 6,040.6 km
- Drive from Santa Ana to Panama Citycar 6,040.6 km
3d 5h$827–1,194Train to Los Angeles International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Tocumen International Airport (PTY)plane LAX - PTY
11h 17m$474–621
John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Panama City is to train and fly which costs $200 - $700 and takes 11h 24m.
The fastest way to get from Santa Ana to Panama City is to fly which takes 9h 37m and costs $230 - $800.
The distance between Santa Ana and Panama City is 4820 km. The road distance is 6040.6 km.
The best way to get from Santa Ana to Panama City without a car is to train and bus which takes 5 days 8h and costs $410 - $600.
It takes approximately 9h 37m to get from Santa Ana to Panama City, including transfers.
Panama City is 2h ahead of Santa Ana. It is currently 8:18 AM in Santa Ana and 10:18 AM in Panama City.
Yes, the driving distance between Santa Ana to Panama City is 6041 km. It takes approximately 3 days 5h to drive from Santa Ana to Panama City.
There are 866+ hotels available in Panama City.
What companies run services between Santa Ana, CA, USA and Panama City, Panama?
United Airlines, Copa Airlines, and Southwest Airlines fly from John Wayne Airport Orange County (SNA) to Tocumen International Airport (PTY) 3 times a day.
- Website
- copaair.com
Flights from John Wayne Airport Orange County to Tocumen International Airport via San Jose Cabo
- Ave. Duration
- 8h 40m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $170–700
Flights from John Wayne Airport Orange County to Tocumen International Airport via Austin
- Ave. Duration
- 8h 55m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $170–700
Flights from John Wayne Airport Orange County to Tocumen International Airport via Denver
- Ave. Duration
- 9h 58m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $190–800
Flights from John Wayne Airport Orange County to Tocumen International Airport via Las Vegas
- Ave. Duration
- 10h 5m
- When
- Sunday
- Estimated price
- $170–750
Flights from Los Angeles International Airport to Tocumen International Airport
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $140–600
Flights from San Diego International Airport to Tocumen International Airport
- Ave. Duration
- 6h 13m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $140–600
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $8–21
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $8–21
- Website
- Amtrak
Train from Santa Ana to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- $21–55
- Website
- Amtrak
- Phone
- +1 213 368 1172
- [email protected]
- Website
- busesusatours.com
Bus from Los Angeles to San Salvador
- Ave. Duration
- 3d 15h
- Frequency
- Once a week
- Estimated price
- $290–380
- Schedules at
- busesusatours.com
Want to know more about travelling around Panama
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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