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How to get fromSanta Ana to Roanokeby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

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There are 6 ways to get from Santa Ana to Roanoke by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane SNA - ROA
    8h 8m
    $212–788

  2. Train to Los Angeles International Airport, fly

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane LAX - ROA
    11h 6m
    $192–691

  3. Bus

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    2d 11h
    $425–838

  4. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Charlottesvilletrain train
    3. Take the train from Charlottesville to Roanoketrain train
    2d 21h
    $1,002–2,134

  5. Drive 2,419.1 mi

    1. Drive from Santa Ana to Roanokecar car 2,419.1 mi
    38h 32m
    $442–638

  6. Train, bus

    1. Take the train from Pomona Amtrak to St. Louistrain train
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    3d 3h
    $863–1,843

Santa Ana to Roanoke by bus

Calendar7Weekly Buses
Duration2d 11hAverage Duration
Ticket$425Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Roanoke.ExpandLaunch map view
  • Distance: 2,144.6 mi
  • Duration: 8h 8m

What companies run services between Santa Ana, CA, USA and Roanoke, VA, USA?

Delta, United Airlines, and American Airlines fly from John Wayne Airport Orange County (SNA) to Roanoke Regional Airport-Woodrum Field (ROA) 4 times a day. Alternatively, you can take a bus from Santa Ana to Roanoke Bus Stop via Los Angeles Union Station, St Louis Bus Station, and Nashville Bus Station in around 2d 11h.

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