Rome2Rio

How to get fromSanta Ana to San Isidroby bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

Find Transport to San Isidro

See all options

There are 5 ways to get from Santa Ana to San Isidro by bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Tijuana

    best
    1. Take the bus from Santa Ana Bus Stop to San Ysidro Bus Terminalbus bus FlixBus 2017 / ...
    2. Take the bus from Tijuana to Mexicalibus bus
    5h 49m
    $918–1,507

  2. Drive 338.8 km

    cheapest
    1. Drive from Santa Ana to San Isidrocar car 338.8 km
    3h 43m
    $650–938

  3. Train, bus

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    2. Take the bus from Tijuana to Mexicalibus bus
    6h 31m
    $1,147–2,182

  4. Train, fly, drive

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Imperial County Airport (IPL)plane plane LAX - IPL
    3. Drive from Imperial County Airport (IPL) to San Isidrocar car
    4h 55m
    $1,778–10,724

  5. Bus

    1. Take the bus from Santa Ana to Tijuana - Plaza El Mexicanobus bus Los Angeles
    2. Take the bus from Tijuana to Mexicalibus bus
    7h 20m
    $893–1,934

Los Angeles International Airport (LAX) to Imperial County Airport (IPL) flights

Calendar17Weekly Planes
Duration1h 25mAverage Duration
Ticket$1,447Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santa Ana to San Isidro.ExpandLaunch map view
  • Distance: 361 km
  • Duration: 5h 49m

What companies run services between Santa Ana, CA, USA and San Isidro, Baja California, Mexico?

You can take a bus from Santa Ana Bus Stop to San Isidro via San Ysidro Bus Terminal, Tijuana, and Mexicali in around 5h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Mexico

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound