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How to get fromSanta Ana to San Mateoby plane, bus, train (Amtrak), car, train, subway, tram, or bus (Greyhound)

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There are 7 ways to get from Santa Ana to San Mateo by plane, bus, train (Amtrak), car, train, subway, tram, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2h 12m
    $149–749

  2. Bus via San Jose

    cheapest
    1. Take the bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwichbus bus Westminster
    11h 23m
    $51–70

  3. Train, Caltrain

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to San Josetrain train
    3. Take the train from San Jose Diridon Caltrain Northbound to San Mateo Caltrain Northboundtrain train
    12h 52m
    $148–312

  4. Drive 400.5 mi

    1. Drive from Santa Ana to San Mateocar car 400.5 mi
    6h 45m
    $74–106

  5. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Mateo Caltrain Northboundtrain train
    2h 48m
    $227–845

  6. Fly to Oakland International Airport, BART, tram, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2. Take the subway from Coliseum to Embarcaderosubway subway
    3. Take the tram from Metro Embarcadero Station to King St & 4th Sttram tram
    4. Take the train from San Francisco Caltrain Southbound to San Mateo Caltrain Southboundtrain train
    3h 10m
    $250–800

  7. Bus (Greyhound)

    1. Take the bus from Santa Ana Bus Stop to San Francisco Bus Stationbus bus Greyhound US0831
    11h 48m
    $66–126

Santa Ana to San Mateo by bus

Calendar14Weekly Buses
Duration11h 23mAverage Duration
Ticket$51Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to San Mateo.ExpandLaunch map view
  • Distance: 383.6 mi
  • Duration: 2h 12m

What companies run services between Santa Ana, CA, USA and San Mateo, CA, USA?

Frontier Airlines, Alaska Airlines, Inc., and two other airlines fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO) hourly. Alternatively, Hoang Express operates a bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich once daily. Tickets cost $45–60 and the journey takes 6h 45m. Xe Do Hoang Transportation also services this route once daily.

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