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How to get fromSanta Ana to South Carolinaby plane, taxi, train (Amtrak), car, or train

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There are 7 ways to get from Santa Ana to South Carolina by plane, taxi, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Charlotte Douglas International Airport, taxi

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT)plane plane SNA - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 36m
    $358–1,233

  2. Train to Los Angeles International Airport, fly to Charlotte Douglas International Airport, taxi

    cheapest
    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Charlotte Douglas International Airport (CLT)plane plane LAX - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    8h 12m
    $268–556

  3. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3d 1h
    $1,137–2,399

  4. Drive 2,441.8 mi

    1. Drive from Santa Ana to Charlestoncar car 2,441.8 mi
    39h 43m
    $446–644

  5. Fly John Wayne Airport Orange County to Greenville–Spartanburg International Airport

    1. Fly from John Wayne Airport Orange County (SNA) to Greenville–Spartanburg International Airport (GSP)plane plane SNA - GSP
    6h 56m
    $313–1,078

  6. Fly John Wayne Airport Orange County to Columbia

    1. Fly from John Wayne Airport Orange County (SNA) to Columbia (CAE)plane plane SNA - CAE
    8h 24m
    $460–1,835

  7. Train to San Diego International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Charlotte Douglas International Airport (CLT)plane plane SAN - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    8h 39m
    $339–1,109

John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT) flights

Calendar75Weekly Planes
Duration7h 10mAverage Duration
Ticket$257Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to South Carolina.ExpandLaunch map view
  • Distance: 2,127.3 mi
  • Duration: 5h 36m

What companies run services between Santa Ana, CA, USA and South Carolina, USA?

You can take a train from Santa Ana to Charleston via Fullerton Amtrak Station, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 3d 1h. Alternatively, Delta, American Airlines, and United Airlines fly from John Wayne Airport Orange County (SNA) to Greenville–Spartanburg International Airport (GSP) every 4 hours.

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