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How to get fromSanta Ana to Tampaby plane, bus, train, car, bus (Greyhound, Flixbus), or train (Amtrak)

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There are 8 ways to get from Santa Ana to Tampa by plane, bus, train, car, bus (Greyhound, Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Tampa (TPA)plane plane SNA - TPA
    7h 46m
    $200–785

  2. Train to San Diego International Airport, fly

    cheapest
    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Tampa (TPA)plane plane SAN - TPA
    9h 9m
    $176–705

  3. Bus via Ciudad Juárez

    1. Take the bus from Santa Ana to El Pasobus bus Cbx
    2. Take the bus from El Paso, TX - Tornado Bus Co to Houston, TX - Houston Airline Drbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Ruskinbus bus
    2d 5h
    $448–568

  4. Train, bus

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Houstontrain train
    3. Take the bus from Houston - Harrisburg Blvd to Ruskinbus bus
    2d 12h
    $598–1,231

  5. Drive 2,437.7 mi

    1. Drive from Santa Ana to Tampacar car 2,437.7 mi
    40h 15m
    $445–643

  6. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Tampa (TPA)plane plane LAX - TPA
    8h 25m
    $178–686

  7. Bus

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    2d 11h
    $380–733

  8. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tampatrain train
    3d 13h
    $1,037–2,509

Santa Ana to Tampa by bus

Calendar7Weekly Buses
Duration2d 11hAverage Duration
Ticket$380Cheapest Price
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Questions & Answers

Map of how to get from Santa Ana to Tampa.ExpandLaunch map view
  • Distance: 2,135.6 mi
  • Duration: 7h 46m

What companies run services between Santa Ana, CA, USA and Tampa, FL, USA?

Southwest Airlines, United Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Tampa (TPA) every 2 hours. Alternatively, you can take a bus from Santa Ana to Marion St @ Kennedy Blvd via El Paso, El Paso, TX - Tornado Bus Co, Houston, TX - Houston Airline Dr, Theater District Rusk EB, Magnolia Park Transit Center EB, Houston - Harrisburg Blvd, Ruskin, US Hwy 41 @ Shell Point Rd, Providence Rd @ Providence Park, and Providence Rd @ Providence Oaks Dr in around 2d 5h.

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