There are 10 ways to get from Santa Ana to Zacatecas by bus, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Tijuana International Airport, fly to Zacatecas International Airport
best- Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus
- Fly from Tijuana International Airport (TIJ) to Zacatecas International Airport (ZCL)plane TIJ - ZCL
7h 19m$4,275–10,952Bus
cheapest- Take the bus from Disneyland Employee's Entrance to 6th / Los Angelesbus 460
- Take the bus from Los Angeles to Mazatlánbus
- Take the bus from Mazatlán to Zacatecasbus
43h 56m$2,695–3,805Train, bus
- Take the train from Santa Ana to San Bernardino - Downtowntrain
- Take the bus from San Bernardino to El Pasobus La
- Take the bus from El Paso to Zacatecasbus
33h 14m$3,969–6,029Train, bus via San Antonio
- Take the train from Santa Ana to Los Angelestrain
- Take the train from Los Angeles to San Antonio Stationtrain
- Take the bus from San Antonio to Zacatecasbus
45h 53m$8,276–18,083Drive 2,292 km
- Drive from Santa Ana to Zacatecascar 2,292 km
26h 10m$4,673–6,750Train to Los Angeles International Airport, fly to Zacatecas International Airport
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Zacatecas International Airport (ZCL)plane LAX - ZCL
7h 10m$5,182–13,239Bus to Tijuana International Airport, fly to Lic. Jesús Terán Peredo International Airport, bus
- Take the bus from Santa Ana to Tijuana Aeropuerto, B.C.bus
- Fly from Tijuana International Airport (TIJ) to Lic. Jesús Terán Peredo International Airport (AGU)plane TIJ - AGU
- Take the bus from Aguascalientes to Zacatecasbus
9h 58m$3,395–6,132Train to Los Angeles International Airport, fly to Lic. Jesús Terán Peredo International Airport, bus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Lic. Jesús Terán Peredo International Airport (AGU)plane LAX - AGU
- Take the bus from Aguascalientes to Zacatecasbus
9h 50m$4,002–16,319Bus via Ciudad Juárez
- Take the bus from Santa Ana to Huntington Parkbus 2
- Take the bus from 2474 E Florence Ave - Huntington Park to El Pasobus
- Take the bus from El Paso to Zacatecasbus
35h 30m$4,720–6,603Train, bus #2
- Take the train from Santa Ana to San Diegotrain
- Take the bus from Tijuana to Aguascalientesbus
- Take the bus from Aguascalientes to Zacatecasbus
44h 38m$5,183–10,364
Santa Ana to Zacatecas by train, foot, and bus
Comparing Your Travel Options
The cheapest way to get from Santa Ana to Zacatecas is to bus which costs $2600 - $3800 and takes 43h 56m.
The fastest way to get from Santa Ana to Zacatecas is to train and fly which takes 7h 10m and costs $5000 - $14000.
No, there is no direct bus from Santa Ana to Zacatecas. However, there are services departing from Santa Ana and arriving at Zacatecas via 2474 E Florence Ave - Huntington Park and El Paso. The journey, including transfers, takes approximately 35h 30m.
The distance between Santa Ana and Zacatecas is 1974 km. The road distance is 2292 km.
The best way to get from Santa Ana to Zacatecas without a car is to train and bus which takes 33h 14m and costs $3900 - $6500.
It takes approximately 7h 19m to get from Santa Ana to Zacatecas, including transfers.
Santa Ana to Zacatecas bus services, operated by Limousine Express, depart from Santa Ana station.
Santa Ana to Zacatecas bus services, operated by Limousine Express, arrive at Huntington Park station.
Zacatecas is 1h ahead of Santa Ana. It is currently 5:14 PM in Santa Ana and 6:14 PM in Zacatecas.
Yes, the driving distance between Santa Ana to Zacatecas is 2292 km. It takes approximately 26h 10m to drive from Santa Ana to Zacatecas.
What companies run services between Santa Ana, CA, USA and Zacatecas, Mexico?
You can take a bus from Santa Ana to Zacatecas via 2474 E Florence Ave - Huntington Park and El Paso in around 35h 30m.
- Website
- volaris.com
Flights from Tijuana International Airport to Zacatecas International Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $3,200–9,500
Flights from Los Angeles International Airport to Zacatecas International Airport
- Ave. Duration
- 2h 57m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $4,400–12,000
Flights from Tijuana International Airport to Lic. Jesús Terán Peredo International Airport
- Ave. Duration
- 2h 46m
- When
- Every day
- Estimated price
- $2,400–4,600
Flights from Los Angeles International Airport to Lic. Jesús Terán Peredo International Airport
- Ave. Duration
- 3h 6m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $3,300–15,000
- Phone
- (800) 371-LINK (5465)
- Website
- Metrolink Trains
Train from Santa Ana to San Bernardino - Downtown
- Ave. Duration
- 1h 24m
- Frequency
- 3 times a day
- Estimated price
- $160–230
- Website
- Metrolink Trains
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Santa Ana to Tijuana Aeropuerto, B.C.
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $550–800
- Website
- Limousine Express
- One Way
- $550–800
Bus from San Bernardino to El Paso
- Ave. Duration
- 12h 30m
- Frequency
- Every 4 hours
- Estimated price
- $1,600–2,400
- Website
- Limousine Express
- One Way
- $1,600–2,400
Bus from Santa Ana to Tijuana Aeropuerto, B.C.
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $550–800
- Website
- Limousine Express
- One Way
- $550–800
Bus from Santa Ana to Huntington Park
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $430–650
- Website
- Limousine Express
- One Way
- $430–650
Want to know more about travelling around Mexico
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 60+ hotels available in Zacatecas.






