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How to get fromSanta Clara to Des Moinesby plane, bus (Greyhound, Flixbus), train, bus, car, shuttle, or subway

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There are 10 ways to get from Santa Clara to Des Moines by plane, bus (Greyhound, Flixbus), train, bus, car, shuttle, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Norman Y. Mineta San José International Airport

    best
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Des Moines (DSM)plane plane SJC - DSM
    6h 48m
    $220–924

  2. Bus

    1. Take the bus from San Jose Diridon Station to Oaklandbus bus
    2. Take the bus from Oakland to Sparks Transit Centerbus bus
    3. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Des Moinesbus bus
    44h 31m
    $290–584

  3. Train, bus via Denver

    1. Take the train from Santa Clara Amtrak to Emeryvilletrain train
    2. Take the train from Emeryville to Denvertrain train
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    2d 1h
    $545–1,131

  4. Drive 1,824.4 mi

    1. Drive from Santa Clara to Des Moinescar car 1,824.4 mi
    27h 55m
    $333–481

  5. Train to Oakland International Airport, fly

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to Des Moines (DSM)plane plane OAK - DSM
    7h 24m
    $241–998

  6. Caltrain to San Francisco International Airport, fly

    1. Take the train from Santa Clara Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to Des Moines (DSM)plane plane SFO - DSM
    7h 32m
    $222–691

  7. Train to Sacramento International Airport, fly

    1. Take the train from Santa Clara Amtrak to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Des Moines (DSM)plane plane SMF - DSM
    10h 13m
    $271–1,061

  8. Shuttle to Monterey Regional Airport, fly

    1. Take a shuttle bus from SJC Airport Terminal A to Monterey Shuttle Stationshuttle bus
    2. Fly from Monterey Regional Airport (MRY) to Des Moines (DSM)plane plane MRY - DSM
    9h 28m
    $279–981

  9. BART, train, bus

    1. Take the subway from Milpitas to Richmondsubway subway
    2. Take the train from Richmond to Denvertrain train
    3. Take the bus from Denver to Omaha, NEbus bus
    4. Take the bus from Omaha, NE to Des Moinesbus bus
    2d 2h
    $610–1,137

  10. Train, bus

    1. Take the train from San Jose to Los Angelestrain train
    2. Take the train from Los Angeles to Kansas Citytrain train
    3. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    2d 4h
    $713–1,546

Santa Clara to Des Moines by train and bus

Calendar14Weekly Services
Duration44h 31mAverage Duration
Ticket$290Cheapest Price
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Questions & Answers

Map of how to get from Santa Clara to Des Moines.ExpandLaunch map view
  • Distance: 1,539.5 mi
  • Duration: 6h 48m

What companies run services between Santa Clara, CA, USA and Des Moines, IA, USA?

United Airlines, Southwest Airlines, and two other airlines fly from Norman Y. Mineta San José International Airport (SJC) to Des Moines (DSM) every 4 hours. Alternatively, you can take a train from Santa Clara Caltrain Southbound to Des Moines via San Jose Diridon Caltrain Southbound, San Jose Diridon Station, Oakland, Sparks Transit Center, and Denver Union Station in around 44h 31m.

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