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How to get fromSanta Clara to Knoxvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

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There are 8 ways to get from Santa Clara to Knoxville by plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Norman Y. Mineta San José International Airport to Mcghee Tyson Airport

    best
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Mcghee Tyson Airport (TYS)plane plane SJC - TYS
    8h 4m
    $358–1,372

  2. Fly Norman Y. Mineta San José International Airport to Nashville, drive

    cheapest
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Nashville (BNA)plane plane SJC - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 17m
    $192–752

  3. Bus

    1. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus
    3d 17h
    $667–1,209

  4. Train, bus

    1. Take the train from Santa Clara Amtrak to Emeryvilletrain train
    2. Take the train from Emeryville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 17h
    $1,142–2,443

  5. Drive 2,426.7 mi

    1. Drive from Santa Clara to Knoxvillecar car 2,426.7 mi
    38h 48m
    $443–640

  6. Caltrain to San Francisco International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Santa Clara Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to Mcghee Tyson Airport (TYS)plane plane SFO - TYS
    8h 47m
    $330–1,190

  7. Train to Oakland International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to Mcghee Tyson Airport (TYS)plane plane OAK - TYS
    8h 39m
    $378–1,397

  8. Shuttle to Monterey Regional Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from SJC Airport Terminal A to Monterey Shuttle Stationshuttle bus
    2. Fly from Monterey Regional Airport (MRY) to Mcghee Tyson Airport (TYS)plane plane MRY - TYS
    11h 1m
    $407–1,430

Norman Y. Mineta San José International Airport (SJC) to Mcghee Tyson Airport (TYS) flights

Calendar41Weekly Planes
Duration7h 29mAverage Duration
Ticket$305Cheapest Price
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Questions & Answers

Map of how to get from Santa Clara to Knoxville.ExpandLaunch map view
  • Distance: 2,110.3 mi
  • Duration: 8h 4m

What companies run services between Santa Clara, CA, USA and Knoxville, TN, USA?

United Airlines, Southwest Airlines, and two other airlines fly from Norman Y. Mineta San José International Airport (SJC) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a train from Santa Clara Caltrain Southbound to Knoxville via San Jose Diridon Caltrain Southbound, San Jose Diridon Station, Los Angeles Union Station, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 3d 17h.

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