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How to get fromSanta Clara to St. Louisby plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

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There are 9 ways to get from Santa Clara to St. Louis by plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Norman Y. Mineta San José International Airport

    best
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Lambert–St. Louis International Airport (STL)plane plane SJC - STL
    7h 26m
    $196–806

  2. Caltrain to San Francisco International Airport, fly

    cheapest
    1. Take the train from Santa Clara Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL)plane plane SFO - STL
    6h 33m
    $148–453

  3. Bus

    1. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus Greyhound US0831 / ...
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus Greyhound US1210
    2d 1h
    $334–656

  4. Train, bus (Amtrak)

    1. Take the train from Santa Clara Amtrak to Emeryvilletrain train
    2. Take the train from Emeryville to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    4. Take the train from Springfield to St. Louistrain train
    2d 9h
    $780–1,651

  5. Drive 2,077.3 mi

    1. Drive from Santa Clara to St. Louiscar car 2,077.3 mi
    32h 22m
    $380–548

  6. Train to Oakland International Airport, fly

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to Lambert–St. Louis International Airport (STL)plane plane OAK - STL
    8h 11m
    $217–880

  7. Train to Sacramento International Airport, fly

    1. Take the train from Santa Clara Amtrak to Sacramentotrain train
    2. Fly from Sacramento International Airport (SMF) to Lambert–St. Louis International Airport (STL)plane plane SMF - STL
    9h 19m
    $257–793

  8. Shuttle to Monterey Regional Airport, fly

    1. Take a shuttle bus from SJC Airport Terminal A to Monterey Shuttle Stationshuttle bus
    2. Fly from Monterey Regional Airport (MRY) to Lambert–St. Louis International Airport (STL)plane plane MRY - STL
    10h 8m
    $245–913

  9. Bus, train

    1. Take the bus from San Jose - Huong Lan Sandwich to Chinatown Metro Station - Los Angeles, CAbus bus San Jose
    2. Take the train from Los Angeles to St. Louistrain train Texas Eagle
    2d 16h
    $800–1,659

Santa Clara to St. Louis by train and bus

Calendar14Weekly Services
Duration2d 1hAverage Duration
Ticket$334Cheapest Price
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Questions & Answers

Map of how to get from Santa Clara to St. Louis.ExpandLaunch map view
  • Distance: 1,729.4 mi
  • Duration: 7h 26m

What companies run services between Santa Clara, CA, USA and St. Louis, MO, USA?

Southwest Airlines, United Airlines, and Delta fly from Norman Y. Mineta San José International Airport (SJC) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a train from Santa Clara Caltrain Southbound to St Louis Bus Station via San Jose Diridon Caltrain Southbound, San Jose Diridon Station, and Los Angeles Union Station in around 2d 1h.

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