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How to get fromSanta Clarita to La Mesaby train (Amtrak), train, bus, car, plane, tram, or bus (Amtrak)

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There are 5 ways to get from Santa Clarita to La Mesa by train (Amtrak), train, bus, car, plane, tram, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Newhall to L.A. Union Stationtrain train AV Line
    2. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    5h 10m
    $45–110

  2. Drive 154.3 mi

    cheapest
    1. Drive from Santa Clarita to La Mesacar car 154.3 mi
    2h 45m
    $29–41

  3. Train, bus

    1. Take the train from Newhall to L.A. Union Stationtrain train AV Line
    2. Take the bus from Los Angeles Downtown to San Diegobus bus FlixBus 2006 / ...
    6h 28m
    $30–60

  4. Train, fly, tram

    1. Take the train from Newhall to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane plane LAX - SAN
    3. Take the tram from Civic Center Station to La Mesa Blvd Stationtram tram
    5h 7m
    $179–694

  5. Bus

    1. Take the bus from Santa Clarita-Newhall Amtrak Station to Van Nuysbus bus Amtrak Thruway Connecting Service
    2. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus bus reLAXsan
    8h
    $75–147

Santa Clarita to La Mesa by train, foot, and tram

Calendar84Weekly Services
Duration5h 10mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Santa Clarita to La Mesa.ExpandLaunch map view
  • Distance: 164.4 mi
  • Duration: 5h 10m

What companies run services between Santa Clarita, CA, USA and La Mesa, CA, USA?

You can take a train from Newhall to 70th Street Station via L.A. Union Station, Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 5h 10m. Alternatively, you can take a bus from Santa Clarita-Newhall Amtrak Station to University Av & Allison Av via Van Nuys, Van Nuys / Keswick, Woodley / Saticoy, Van Nuys FlyAway Terminal - 7610 Woodley Ave, LAX Tom Bradley International Terminal, LAX Terminal 3 Shared Rides Stop, San Diego, Old Town Transit Center, and University Av & College Av in around 8h.

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