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How to get fromSanta Clarita to Otay Mesaby train (Amtrak), bus, car, train, plane, or tram

Find Transport to Otay Mesa

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There are 5 ways to get from Santa Clarita to Otay Mesa by train (Amtrak), bus, car, train, plane, or tram

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Newhall to L.A. Union Stationtrain train AV Line
    2. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    5h 57m
    $47–113

  2. Drive 167.4 mi

    cheapest
    1. Drive from Santa Clarita to Otay Mesacar car 167.4 mi
    3h
    $31–45

  3. Bus

    1. Take the bus from Los Angeles - Pacoima to San Ysidrobus bus San Jose
    6h 51m
    $51–91

  4. Train, fly, tram, line 905 bus

    1. Take the train from Newhall to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane plane LAX - SAN
    3. Take the tram from Civic Center Station to Iris Avenue Stationtram tram
    4. Take the bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rdbus bus
    5h 24m
    $181–698

  5. Train, bus

    1. Take the train from Newhall to L.A. Union Stationtrain train AV Line
    2. Take the bus from Los Angeles Downtown to San Diegobus bus FlixBus 2006 / ...
    7h 15m
    $32–63

Santa Clarita to Otay Mesa by train, foot, tram, and bus

Calendar84Weekly Services
Duration5h 57mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Santa Clarita to Otay Mesa.ExpandLaunch map view
  • Distance: 175 mi
  • Duration: 5h 57m

What companies run services between Santa Clarita, CA, USA and Otay Mesa, CA, USA?

You can take a train from Newhall to Otay Mesa Rd & Cactus Rd via L.A. Union Station, Los Angeles, San Diego Old Town Transportation Center, Old Town Station, Iris Avenue Station, and Iris Avenue Transit Center in around 5h 57m. Alternatively, Tufesa operates a bus from Los Angeles - Pacoima to San Ysidro once daily. Tickets cost $40–70 and the journey takes 4h 20m.

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