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How to get fromSanta Cruz to Santiagoby plane, bus, or car

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There are 5 ways to get from Santa Cruz to Santiago by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Puerto Natales

    best
    1. Fly from Puerto Natales (PNT) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane PNT - SCL
    3h 38m
    $79–258

  2. Bus via Bariloche

    1. Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus Barilochebus bus El Chalten
    2. Take the bus from Bariloche to Terminal Surbus bus Bariloche / ...
    42h 49m
    $155–296

  3. Drive 2,705.2 km

    1. Drive from Río Gallegos to Santiagocar car 2,705.2 km
    31h 44m
    $334–482

  4. Fly from Piloto Civil Norberto Fernández International Airport

    1. Fly from Piloto Civil Norberto Fernández International Airport (RGL) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane RGL - SCL
    7h 44m
    $278–962

  5. Bus

    1. Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal Río Cuartobus bus
    2. Take the bus from Terminal Río Cuarto to Terminal Mendozabus bus
    3. Take the bus from Terminal Mendoza to Terminal Alameda - Turbusbus bus
    2d 4h
    $212–416

Puerto Natales (PNT) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

Calendar10Weekly Planes
Duration3h 37mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Santiago.ExpandLaunch map view
  • Distance: 2,076 km
  • Duration: 3h 38m

What companies run services between Santa Cruz, Argentina and Santiago, Chile?

Sky Airline and LATAM Chile fly from Puerto Natales (PNT) to Comodoro Arturo Merino Benítez International Airport (SCL) once daily. Alternatively, you can take a vehicle from Río Gallegos to Pajaritos Dirección San Pablo via Terminal de Ómnibus de Río Gallegos, Bariloche, Terminal Sur, and Universidad de Santiago Dirección San Pablo in around 42h 49m.

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