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How to get fromSanta Cruz to Uyuniby plane, bus, shuttle, or car

Find Transport to Uyuni

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There are 7 ways to get from Santa Cruz to Uyuni by plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Puerto Natales to Uyuni Airport

    best
    1. Fly from Puerto Natales (PNT) to Uyuni Airport (UYU)plane plane PNT - UYU
    25h 32m
    $379–1,213

  2. Drive 4,040.5 km

    cheapest
    1. Drive from Río Gallegos to Uyunicar car 4,040.5 km
    45h 30m
    $360–520

  3. Bus, Tour

    1. Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus de General Guemesbus bus
    2. Take the bus from Terminal de Omnibus de General Guemes to Terminal de Saltabus bus
    3. Take a shuttle bus from Salta to Uyunishuttle bus
    2d 11h
    $556–738

  4. Fly Puerto Natales to Calama Airport, shuttle, Tour

    1. Fly from Puerto Natales (PNT) to Calama Airport (CJC)plane plane PNT - CJC
    2. Take a shuttle bus from Calama Airport to San Pedro de Atacamashuttle bus
    3. Take a shuttle bus from San Pedro de Atacama to Uyunishuttle bus
    12h 2m
    $553–815

  5. Fly El Calafate to Uyuni Airport

    1. Fly from El Calafate (FTE) to Uyuni Airport (UYU)plane plane FTE - UYU
    24h 54m
    $634–1,742

  6. Fly El Calafate to Alcantari Airport, bus

    1. Fly from El Calafate (FTE) to Alcantari Airport (SRE)plane plane FTE - SRE
    2. Take the bus from Sucre to Uyunibus bus
    21h 34m
    $458–1,392

  7. Bus, Tour via Esquel

    1. Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal De Ómnibus Esquelbus bus
    2. Take the bus from Esquel to Terminal de Omnibus de General Guemesbus bus
    3. Take the bus from Terminal de Omnibus de General Guemes to Terminal de Saltabus bus
    4. Take a shuttle bus from Salta to Uyunishuttle bus
    2d 21h
    $521–758

Puerto Natales (PNT) to Uyuni Airport (UYU) flights

Calendar3Weekly Planes
Duration30h 31mAverage Duration
Ticket$372Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santa Cruz to Uyuni.ExpandLaunch map view
  • Distance: 3,535.8 km
  • Duration: 25h 32m

What companies run services between Santa Cruz, Argentina and Uyuni, Potosí, Bolivia?

LATAM Chile and Boliviana de Aviación fly from Puerto Natales (PNT) to Uyuni Airport (UYU) 3 times a week.

Airlines
Bus operators

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