There are 3 ways to get from Santa Cruz to Cusco by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Viru Viru International Airport (VVI) to Alejandro Velasco Astete International Airport (CUZ)plane VVI - CUZ
5h 48m$281–551Bus
cheapest- Take the bus from Santa Cruz to La Pazbus La Paz
- Take the bus from La Paz to Cuscobus La Paz
33h 4m$53–101Drive 1,423.3 km
- Drive from Santa Cruz de la Sierra to Cuscocar 1,423.3 km
21h 43m$214–309
Viru Viru International Airport (VVI) to Alejandro Velasco Astete International Airport (CUZ) flights
Comparing Your Travel Options
The cheapest way to get from Santa Cruz to Cusco is to bus which costs $50 - $110 and takes 33h 4m.
The fastest way to get from Santa Cruz to Cusco is to fly which takes 5h 48m and costs $280 - $550.
No, there is no direct bus from Santa Cruz to Cusco. However, there are services departing from Santa Cruz and arriving at Cusco via La Paz. The journey, including transfers, takes approximately 33h 4m.
The distance between Santa Cruz and Cusco is 1066 km. The road distance is 1423.3 km.
The best way to get from Santa Cruz to Cusco without a car is to bus which takes 33h 4m and costs $50 - $110.
It takes approximately 5h 48m to get from Santa Cruz to Cusco, including transfers.
Santa Cruz to Cusco bus services, operated by Trans Copacabana SA, depart from Santa Cruz station.
The best way to get from Santa Cruz to Cusco is to fly which takes 5h 48m and costs $280 - $550. Alternatively, you can bus, which costs $50 - $110 and takes 33h 4m.
Santa Cruz to Cusco bus services, operated by Trans Copacabana SA, arrive at La Paz station.
Cusco is 1h behind Santa Cruz. It is currently 4:10 PM in Santa Cruz and 3:10 PM in Cusco.
What companies run services between Santa Cruz, Bolivia and Cusco, Peru?
LATAM Chile, Boliviana de Aviación, and Avianca - Aerovías del Continente Americano S.A. fly from Viru Viru International Airport (VVI) to Alejandro Velasco Astete International Airport (CUZ) 3 times a day. Alternatively, you can take a vehicle from Santa Cruz de la Sierra to Cusco via Santa Cruz and La Paz in around 33h 4m.
- Website
- latam.com
Flights from Viru Viru International Airport to Alejandro Velasco Astete International Airport via Lima
- Ave. Duration
- 5h 40m
- When
- Monday, Thursday, Friday, Saturday, Wednesday, and Sunday
- Estimated price
- $270–600
- Phone
- +591-72233555
- [email protected]
- Website
- Trans Copacabana SA
Bus from Santa Cruz to La Paz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $18–24
- Schedules at
- Trans Copacabana SA
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Booking & Getting There
Yes, the driving distance between Santa Cruz to Cusco is 1423 km. It takes approximately 21h 43m to drive from Santa Cruz to Cusco.
There are 1446+ hotels available in Cusco.